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Skin Brightening and Pigmentation Care

Discover our curated collection of K-Derma products designed to brighten your skin, reduce pigmentation, and even out your skin tone. Achieve a radiant and flawless complexion with our effective solutions.

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Authentic SYNERFILL Skin Booster HA PDRN PN Skin Regeneration Anti-aging Korea Wholesale

SYNERFILL Skin Booster (5mL × 1 Vial)

$66.00

SYNERFILL Skin Booster Product Detail

Product Identification

SYNERFILL Skin Booster

HA + PDRN + PN Complex

Monica Non-crosslinked HA Cell Regeneration

Total Volume/Content

5mL × 1 Vial

Formulation Type

Liquid solution

Core Ingredients & Technology

Primary Active Ingredients (Per 5mL)

H-HA (High molecular weight HA): 67.5mg
L-HA (Low molecular weight HA): 67.5mg
PDRN (Polydeoxyribonucleotide): 5mg
PN (Polynucleotide): 5mg

Mechanism of Action

H-HA & L-HA provide intense moisture, enhance skin elasticity, and maintain long-lasting volume. PDRN & PN promote cell regeneration, offer anti-inflammatory effects, enhance wound healing, and repair broken collagen and elastin fibers.

FDA Proven Safety No Residues Lifting & Regeneration

Efficacy & Benefits

Main Effects

Hydration & Volume: Intense moisturizing and long-lasting volume support.
Rejuvenation: Wrinkle reduction, collagen & elastin regeneration.
Healing & Tone: Anti-inflammatory wound healing, whitening, and scar/acne improvement.

Recommended Areas

Full face (Forehead, Cheek, Jaw, Chin, Hollow temple, Tear troughs, Nasolabial folds, Marionette lines, Bunny lines, Mental crease, Jowls), Neck, and Back of hand.

Usage Protocol

Injection Protocols

Method	Target Layer	Depth & Tool	Amount per Point
Dermis Injection	Dermis (17 points per side)	2mm Depth (34G x 2mm needle)	0.25cc – 0.3cc
BAP Point Injection	Subcutaneous fat	4mm – 6mm Depth	0.4cc – 0.5cc

Preparation for BAP Injection When performing the BAP point injection, dilute the product by injecting 1.0mL of normal saline into the 5mL vial solution.

Treatment Cycle & Duration

Cycle: 3 treatments at 2-week intervals.
Onset: Rapid onset with PDRN/PN action visible in 1-2 weeks.
Duration: Overall effect lasts 4 to 8 months.

SYNERFILL Series Comparison

Product Line	Core Ingredients	Primary Focus
SYNERFILL Skin Booster	PDRN + PN + HA Complex	Skin texture, deep hydration, wound healing, overall cell regeneration.
SYNERFILL Face & Body	PLLA + HA Hybrid	Deep volume replenishment and structural lifting.

Storage & Handling

Storage Conditions

Room temperature (1–30°C). Store in a cool, dry place away from direct sunlight. Do not freeze.

Usage Note

Single-use vial. Discard any remaining solution after opening.

Safety Information

Contraindications Pregnancy, breastfeeding, hypersensitivity to HA or salmon-derived DNA (PDRN/PN), and active skin infections at the injection site.

Safety Warnings Strictly for professional medical use. Do not inject intravascularly.

Side Effects & Post-Care

Common Effects: Mild swelling, redness, bruising, tenderness, or temporary papules (bumps) at injection sites.
Post-Care: Avoid heavy makeup for 24 hours. Avoid extreme heat (saunas, hot baths) and strenuous exercise for a few days. Apply sunscreen regularly.

Keywords

SYNERFILL Skin Booster H-HA L-HA PDRN PN Skin Regeneration Anti-aging Skin Elasticity Wound Healing BAP technique Monica

Lipotocin Injection Korea Wholesale Authentic

Lipotocin Inj (12mL x 10 Amps)

$52.00

Product Identification

Lipotocin Inj.

High Dose Cinderella Injection

South Korean Manufacturer IV Injection Ampoule

Total Volume/Content

120mL per box (12mL × 10 Ampoules)

Core Ingredients & Technology

Primary Active Ingredients

Thioctic Acid (Alpha-Lipoic Acid) 300mg

Mechanism of Action

Thioctic Acid acts as an antioxidant master, regenerating Vitamin C, E, and Glutathione while scavenging free radicals. It also increases mitochondrial energy expenditure to aid in lipolysis (fat breakdown) and prevents protein glycation to reduce tissue aging.

Thioctic Acid 300mg High Dose Metabolic Activation Anti-Glycation

Efficacy & Benefits

Main Effects

Intensive Anti-Aging: Powerful antioxidant protection against cellular damage.
Skin Brightening: Reduces dullness and improves skin texture ("Baby Face Injection").
Body Slimming: Boosts metabolism to aid in weight loss and reduce edema.
Fatigue Recovery: Improves energy levels and exhaustion.
Diabetic Neuropathy Relief: Relieves sensory abnormalities.

Targeted Use

Systemic IV Drip Skin Tone Improvement Metabolic Boost

Usage Protocol

Dilution Required Do not inject undiluted directly ("IV Push") as it causes vascular pain and potential shock.

Application Method

Intravenous Drip (IV Infusion)

Dilution Protocol

Mix 1 ampoule (12mL) with 100mL – 250mL of Normal Saline.

Infusion Speed

Administer slowly over at least 15–30 minutes.

Treatment Cycle

1–2 times per week; standard course of 10 sessions.

Product Comparison

Product Version	Thioctic Acid Content	Primary Strategy
Lipotocin (High Dose)	300mg / 12mL	Intensive Slimming & Metabolic Boost
Standard Cindella (Low Dose)	25mg / 5mL	Cocktail Maintenance (Mixed with Vit C/Glutathione)

Storage & Handling

Required Storage Temperature

Room temperature (1°C – 30°C)

Light Sensitivity

Strictly Protect from Light. Keep ampoules in the original box until use.

Shelf Life

24–36 months from manufacture date

Precautions & Safety

Contraindications Do not use in children/adolescents or patients with hypersensitivity to Thioctic Acid.

Safety Warnings Rapid infusion can cause headache, nausea, and respiratory distress. Diabetics should monitor glucose levels as Thioctic acid may cause hypoglycemia.

Common Temporary Side Effects

Nausea, vomiting, or gastrointestinal discomfort (rare with slow drip).
Skin rash or itching at the injection site.

Post-Treatment Care

Avoid heavy alcohol consumption as it interferes with metabolic effects.

Keywords

Lipotocin Thioctic Acid 300mg Alpha Lipoic Acid High Dose Cindella Cinderella Injection Fat Burn Injection Antioxidant IV Metabolism Booster

Authentic POLYDIO Polydioxanone PDO 300mg Collagen Stimulator Korea Wholesale

POLYDIO - Polydioxanone (PDO 300mg × 1 Vial)

$77.00

POLYDIO PDO Dermal Filler - Product Details

K-one Pharma Dermal Filler 300mg

POLYDIO

PDO 300mg x 1 Vial

Advanced polydioxanone-based collagen stimulator for long-lasting skin rejuvenation and natural volume restoration.

Biostimulatory filler with 1-2 years lasting effect through natural collagen regeneration

Main Product Image Placeholder

Product Overview

POLYDIO is a revolutionary PDO-based dermal filler that stimulates natural collagen production for sustained aesthetic improvements.

Product Packaging

Product Vial and Packaging

Single vial containing 300mg powder for reconstitution

Mechanism of Action

Collagen Regeneration Process

Visual demonstration of PDO microsphere collagen stimulation

Treatment Applications

Treatment Areas Diagram

Facial areas suitable for POLYDIO application

Composition & Components

Active Ingredients

Polydioxanone (PDO) Carboxymethyl Cellulose (CMC)

Concentration & Ratio

PDO 150mg CMC 150mg Total 300mg

Component Functions

PDO acts as a biocompatible and absorbable synthetic polymer that stimulates natural collagen production. CMC serves as a carrier gel to facilitate proper injection and distribution.

Particle Specifications

Uniform spherical PDO microspheres with particle size range of 10-60μm for optimal tissue integration and collagen stimulation.

PDO Microsphere Structure

Expected Benefits & Functions

Collagen Stimulation

Promotes natural collagen regeneration and skin tissue renewal

Neocollagenesis Fibroblast Activation

Skin Improvement

Enhanced skin elasticity, firmness, and overall texture quality

Elasticity Firmness

Anti-Aging Effects

Reduction of fine lines, wrinkles, and improvement in skin tone

Wrinkle Reduction Pore Refinement

Before Treatment Image

After Treatment Results

Long-term aesthetic benefits are achieved through gradual biodegradation of PDO microspheres over approximately 1 year, during which continuous collagen and elastin production occurs.

Key Benefits Summary

Collagen regeneration and stimulation for natural skin renewal
Improvement of fine lines and wrinkles through tissue remodeling
Enhanced skin elasticity and firmness with lasting results
Pore reduction and overall skin tone improvement
Natural volume restoration without synthetic fillers
Long-lasting effects maintained for 1-2 years post-treatment

Application Protocol

Product Reconstitution

Reconstitute 300mg powder with sterile water for injection using 18G needle

Preparation

Optional lidocaine addition for patient comfort during injection procedure

Injection Technique

Inject into dermal and subcutaneous layers using 26G cannula

Post-Treatment

Monitor for optimal integration and collagen stimulation response

Injection Parameters

Target Layer: Between dermis and subcutaneous area
Recommended Needle: 26G Cannula for injection
Reconstitution: 18G needle for preparation
Application: Single-use vial, immediate use after preparation

Treatment Areas

All facial areas including fine lines and wrinkles
Pore refinement and skin texture improvement
Skin hydration and elasticity enhancement
Overall facial skin tone and volume restoration

Injection Technique Visual Guide

Treatment cycle provides long-lasting effects with results maintained for 1-2 years due to gradual biodegradation and continuous neocollagenesis.

Technical Specifications

300mg

Total Product Weight

10-60μm

Particle Size Range

1-2years

Effect Duration

Component	Concentration	Function	Properties
Polydioxanone (PDO)	150mg	Collagen Stimulator	Biocompatible, Absorbable
Carboxymethyl Cellulose (CMC)	150mg	Carrier Gel	Injectable Suspension
Total Content	300mg	Biostimulator	Powder for Reconstitution

Storage & Handling

Store at room temperature (1-30°C). Protect from direct sunlight. Single-use vial for immediate application after reconstitution.

Biodegradation

PDO degrades into water and carbon dioxide, which are neutral to the body, ensuring safe biocompatibility.

Mechanism of Action

Collagen Production Timeline

Biostimulation Process

PDO microspheres activate fibroblasts upon injection
Gradual biodegradation stimulates collagen synthesis
Continuous neocollagenesis over 12-month period
Enhanced elastin production for improved skin elasticity

The spherical PDO particles integrate with dermal tissue, providing sustained collagen stimulation as they naturally biodegrade.

Safety Information

Professional Use Only — This product is intended for use by qualified medical professionals in appropriate clinical settings.

Contraindications & Precautions

Do not use on inflamed or infected areas
Ensure proper reconstitution before injection
Single-use vial - do not reuse or store after opening
Follow aseptic technique throughout procedure

Post-Treatment Guidelines

Monitor injection sites for normal healing response
Advise patients on appropriate post-care protocols
Schedule follow-up appointments as clinically indicated

Frequently Asked Questions

The aesthetic effects of POLYDIO are maintained for approximately 1-2 years. The PDO microspheres gradually biodegrade over about 1 year, during which they continuously stimulate collagen and elastin production.

Unlike traditional hyaluronic acid fillers, POLYDIO is a biostimulator that works by stimulating the body's natural collagen production rather than simply adding volume. This results in more natural, long-lasting improvements.

Store at room temperature (1-30°C) away from direct sunlight. The powder must be reconstituted with sterile water for injection immediately before use. Each vial is for single use only.

POLYDIO can be used on all facial areas for improvement of fine lines, wrinkles, pores, skin hydration, elasticity, and overall tone. It's injected between the dermis and subcutaneous layers.

Technical Documentation

Product Manual

Clinical Guidelines

Comprehensive injection protocols and safety guidelines

Certificate Documents

Quality Assurance

Manufacturing standards and quality control documentation

Research Data

Clinical Studies

Scientific evidence supporting efficacy and safety profile