Anti-aging and Wrinkle Care

• ECM Direct Replenishment: Directly delivers micronised hADM into the dermis to physically rebuild and remodel the collapsed extracellular matrix structure from its foundation.
• 3D Tissue Scaffold Restoration: Maintains the innate 3D structure of native dermal tissue, supporting natural skin remodeling rather than simple volumization.
• Immune Compatibility: Manufactured using patented AlloClean Technology to minimize immune rejection while preserving the tissue's natural biological architecture.

• Improves overall skin firmness, dermal density, and elasticity
• Reduces fine lines, early wrinkles, and enlarged pores
• Promotes skin regeneration and deep hydration
• Improves skin texture and tone — reduces redness and blemishes

• PLLA (Poly-L-lactic acid): 400mg. Acts as a bio-stimulator triggering fibroblast activity for long-lasting neocollagenesis.
• H-HA (High-molecular-weight HA): 60mg.
• L-HA (Low-molecular-weight HA): 60mg. Provides immediate hydration and acts as a safe carrier/suspension agent for PLLA particles.

Microporous Sphere Technology: Utilizes spherical PLLA particles with internal pores, maximizing the surface area for higher collagen/elastin production and allowing for smoother injections. CMC & Mannitol Free: Uses HA instead of CMC/Mannitol for suspension, adding immediate volumizing impact.

• Deep Volume Replenishment: Immediate volumization (via HA) for large body areas.
• Collagenesis: Sustained stimulation and generation of collagen under the skin (via PLLA).
• Skin Improvement: Smoothing of skin texture, reduction of fine wrinkles, and improved elasticity.

Standard Cycle: 2 to 3 sessions at 1-month intervals.
Duration: Long-lasting PLLA effects maintained for up to 24 months.

To prevent the formation of subcutaneous nodules (granulomas), practitioners strictly recommend the "5-5-5 Rule" for patients: Massage the treated area for 5 minutes, 5 times a day, for 5 days post-treatment to ensure even particle distribution.

• A2A Receptor Activation: PDRN binds to adenosine A2A receptors to exert anti-inflammatory effects and repair damaged tissues.
• Salvage Pathway: Provides nucleosides (DNA precursors) via the salvage pathway to promote rapid DNA synthesis and cell proliferation.
• Growth Factor Stimulation: Promotes the secretion of VEGF and other growth factors to aid angiogenesis and wound healing.

• Tissue Regeneration: Repairs damaged skin barrier, improves skin thickness, and treats ligament/tendon injuries.
• Pore & Scar Reduction: Diminishes acne scars and tightens pores.
• Rapid Healing: Accelerates wound healing and provides anti-inflammatory support.
• Texture Improvement: Enhances overall skin texture and hydration.

• Medical (Systemic/Local): Intramuscular (IM) or Subcutaneous (SC) injection.
• Aesthetic (Off-label): Intradermal (ID) injection (Mesotherapy) or MTS (Microneedling) application to the face.

• Mild pain, redness, or swelling at the injection site.
• Bruising from the needle insertion.

What is Rejuvenex Forte used for?

Rejuvenex Forte is a high-concentration PDRN solution used for tissue regeneration, pore and scar reduction, rapid wound healing with anti-inflammatory support, and overall skin texture improvement.

What is the key ingredient?

The primary active ingredient is Polydeoxyribonucleotide Sodium (PDRN) at 14.06mg per 2.5mL, derived from salmon DNA.

How long do results last?

Visible skin improvements are often noted after 3–4 sessions, and tissue regeneration effects are cumulative. The typical course is 1 session per week for 3–5 weeks.

Who should administer Rejuvenex Forte?

It is an ethical drug (ETC) administered by injection, including intramuscular or subcutaneous injection and aesthetic intradermal (mesotherapy) or MTS application, and should be administered by a qualified medical professional.

Who manufactures Rejuvenex Forte?

Rejuvenex Forte is manufactured by PharmaResearch Co., Ltd.

Juveheal A features a dual growth factor action where EGF repairs the epidermis and FGF2 stimulates the dermis for improved skin density. Adenosine actively encourages collagen production to correct fine lines, while the Lotus water base provides deep hydration and soothing effects.

• Anti-Aging & Wrinkle Improvement: Specifically targets fine lines and deep wrinkles.
• Skin Vitality & Radiance: Restores a healthy glow to tired or aging skin.
• Elasticity Boost: Improves skin firmness and lifting effect.
• Deep Nutrition: Delivers concentrated nutrients to the skin layers.

Full face (especially areas with fine lines like eyes, forehead, nasolabial folds), Neck.

Ready-to-use liquid ampoule (tear off the plastic cap and aluminum seal to open).

Avoid direct sunlight, high temperature, and high humidity.

• Mild redness or irritation may occur, especially if used with MTS/microneedling (subsides within 1-2 days).

• Use a soothing mask (e.g., cooling sheet mask) after application.
• Apply sun protection.

What is Juveheal A used for?

Juveheal A is an anti-aging and wrinkle care ampoule. It targets fine lines and deep wrinkles, restores skin vitality and radiance, boosts elasticity and firmness, and delivers deep nutrition to the skin.

What are the key ingredients?

The primary active ingredients are Adenosine 0.04%, EGF (Rh-Oligopeptide-1), FGF2 (Rh-Polypeptide-1), and Hydrolyzed Collagen, with a Lotus Flower Water base.

How is it applied?

It is a ready-to-use liquid ampoule applied topically after cleansing. It is highly recommended for use with professional devices such as MTS, Derma Pen, or Electroporation to enhance absorption, typically 1 session per week.

Who should administer Juveheal A?

Juveheal A is for external (topical) use only. For enhanced absorption it is used with professional devices such as MTS, Derma Pen, or Electroporation under professional guidance.

Who manufactures Juveheal A?

Juveheal A is manufactured by J MEDICAL Inter Co., Ltd.

• c-PDRN (Cosmetic Polydeoxyribonucleotide): Hydrolyzed DNA from salmon, optimized for skin absorption to repair damaged cells.
• Sodium Hyaluronate (HA): High-quality European hyaluronic acid for intense hydration.

A Double Effect system where HA provides immediate deep hydration and volume support, while c-PDRN penetrates the barrier to stimulate biological regeneration and collagen synthesis.

• Deep Hydration (Hydro-Lifting): Relieves inner skin dryness and provides a radiant "water glow."
• Skin Regeneration: Repairs skin barrier damaged by external irritation or aesthetic procedures (e.g., lasers).
• Texture Improvement: Softens rough skin texture and improves elasticity.
• Soothing: Calms sensitive and tired skin.

Apply to cleansed skin. Highly recommended for use with aesthetic devices such as MTS (Microneedling), Electroporation, or Iontophoresis to enhance penetration.

• Intensive Care: 3–5 sessions at 1–2 week intervals.
• Maintenance: 1 session every 1–2 months.

Mild redness or irritation may occur if used with aggressive MTS, usually subsiding within 24 hours.

What is Rejuvenex Hydro Essence used for?

Rejuvenex Hydro Essence is a hydro-lifting skin booster used for deep hydration and a radiant water glow, skin barrier regeneration (including post-procedure repair), texture improvement, and soothing sensitive or tired skin.

What are the key ingredients?

The primary active ingredients are c-PDRN (Cosmetic Polydeoxyribonucleotide, hydrolyzed salmon DNA) and Sodium Hyaluronate (Hyaluronic Acid).

How is it applied?

It comes in a ready-to-use pre-filled syringe and is applied to cleansed skin. It is highly recommended for use with aesthetic devices such as MTS (Microneedling), Electroporation, or Iontophoresis. Intensive care is 3–5 sessions at 1–2 week intervals.

Who should administer Rejuvenex Hydro Essence?

It is for external (topical) use only. When combined with aesthetic devices such as MTS, Electroporation, or Iontophoresis, it should be used under professional guidance.

Who manufactures Rejuvenex Hydro Essence?

Rejuvenex Hydro Essence is manufactured by PharmaResearch Co., Ltd.

Polynucleotide (PN), derived from salmon DNA, acts as a tissue regeneration activator. It stimulates the synthesis of collagen and elastin in the dermis (Extra Cellular Matrix restoration) and promotes angiogenesis (formation of new blood vessels) to improve skin density and thickness.

Provides comprehensive skin regeneration and wound healing by accelerating the repair of damaged skin. It improves elasticity and reduces fine lines for anti-aging, smooths skin texture while reducing pore size, and strengthens the skin barrier against environmental stress.

Full Face (General skin rejuvenation), Neck wrinkles, areas with acne scars or enlarged pores, and thin/damaged skin requiring regeneration.

Ready-to-use pre-filled syringe. No dilution required.

Store away from direct sunlight. Do not freeze. Single-use only; discard any remaining solution.

• "Embossing" (small raised bumps) - typically subsides within 24–48 hours
• Mild redness (Erythema), swelling, or bruising
• Mild pain or tenderness

• Avoid makeup for at least 6–12 hours
• Avoid saunas, steam rooms, heavy exercise, and alcohol for 3–7 days
• Apply sunscreen and moisturizer regularly

It provides comprehensive skin regeneration and wound healing, improving elasticity, reducing fine lines for anti-aging, smoothing skin texture while reducing pore size, and strengthening the skin barrier.

Its primary active ingredient is Polynucleotide (PN) 2% (20mg/ml), derived from salmon DNA.

Visible improvements typically appear 1–2 weeks after the first session, with effects lasting 6–12 months. A course of 3 to 4 sessions at 2–3 week intervals is recommended.

It is for professional use only and should be administered by licensed medical practitioners.

REJUBEAU PN Healer is manufactured by TRACLE INC.

NAD+ is a vital coenzyme present in all living cells, crucial for mitochondrial function and ATP (energy) production. Applied to the skin, it facilitates cellular energy metabolism, promotes DNA repair, delays cellular senescence, and activates fibroblasts. This molecular-level rejuvenation helps restore the structural integrity of the dermis.

• Deep cellular regeneration.
• Powerful anti-aging and wrinkle reduction.
• Improvement of skin elasticity.
• Restoration of skin vitality and radiance.
• Strengthening of the skin barrier.

Face, neck, décolletage, and the back of the hands (areas primarily showing signs of photoaging and intrinsic aging).

Standard NAD+ skin booster protocols generally recommend 3–5 sessions at 2–4 week intervals.

Store in a cool, dry place away from direct sunlight (typically 1–30°C or refrigerated at 2–8°C, depending on the exact formulation state).

Intended for professional, single-use application. Open vials should be used immediately to prevent oxidation or contamination.

Mild redness (erythema), localized swelling, pinpoint bruising, or tenderness at the injection or microneedling sites.

• Avoid direct sun exposure and apply broad-spectrum sunscreen diligently.
• Refrain from saunas, hot tubs, swimming, and strenuous exercise for at least 48 hours post-treatment.

Hyaluronic Acid, Peptides, Botanical Extracts, and Aloe Vera.

• Fat Reduction: Actively targets and breaks down accumulated fat deposits under the eyes and effectively halts the regeneration of new fat.
• Skin Tightening: Hyaluronic acid and peptides work synergistically to provide deep hydration, promote skin elasticity, tighten under-eye tissue, and lift loose skin.

A clinically tested, non-surgical formula designed to provide quick and visible results with minimal downtime and no significant swelling or bruising.

Dissolves sagging fat deposits, reduces puffiness and dark circles, tightens and lifts loose under-eye skin, and smooths fine lines and wrinkles.

Subcutaneous injection. Depth should be 2~6mm into the fat layer, superficial fascia layer, and under the skin around the eyes. (Can also be applied topically with gentle massage or via microneedling, depending on the practitioner's protocol).

For eye bag treatment, use 1 bottle (2mL) per session, equating to 1mL per side. Utilize 5 injection points per side with a spacing of 0.3~0.5mm between points. Total injection volume must not exceed 5mL.

Single-use vials. Keep away from direct sunlight.

Clinically tested to cause no significant swelling, bruising, or pain, though mild, temporary injection-site reactions may occur.

• Apply ice or a medical repair mask within 30 minutes after treatment to soothe the skin.
• Do not wash or bathe the treated area for 1 week.
• Refrain from strenuous exercise, alcohol consumption, and saunas for 1 week.
• Avoid spicy foods, seafood, and direct sun exposure.
• Do not use ointments, skincare products, or cosmetics on the treated area to prevent infection.

It is a fat-dissolving and skin-tightening booster that dissolves sagging fat deposits, reduces puffiness and dark circles, tightens loose under-eye skin, and smooths fine lines.

Hyaluronic Acid, Peptides, Botanical Extracts, and Aloe Vera.

It provides quick, noticeable results in a short time, with long-lasting effects on puffiness and skin firmness.

Professional application is highly recommended, via subcutaneous injection 2~6mm into the fat layer around the eyes by a qualified practitioner.

Advanced Cross-linked HA creates a stable 3D matrix to lock in moisture and restore elasticity, while Glutathione acts as a powerful antioxidant to brighten skin tone, fade pigmentation, and detoxify tired skin.

• Deep & Long-Lasting Hydration: Locks in moisture for months.
• Radiance & Tone: Brightens skin tone and fades pigmentation (Whitening effect).
• Elasticity & Plumping: Restores firmness and smooths fine lines.
• Detox & Protection: Fights oxidative stress and revitalizes congested skin.

Single-use vials. Discard any remaining solution after opening.

It is a whitening and hydration skin booster that brightens skin tone, fades pigmentation, and delivers deep long-lasting hydration for the face and body.

Cross-linked Hyaluronic Acid (10 mg/mL) and Glutathione (1 mg/mL), combining a moisture-locking HA matrix with antioxidant brightening.

A standard course is 5 sessions total, spaced 2–3 weeks apart.

For external/professional use only, injected by a qualified practitioner using micropapular, nappage, or linear/retrograde techniques.

It is manufactured by Phace Global Co., Ltd.

A synergistic effect of Hydration (HA), Regeneration (PDRN), and Cellular Recharging (NAD+). It acts as a bio-stimulator to activate the skin's natural healing and energy production cycles.

• Deep Hydration & Glow: Provides an instant moisture boost and "water glow" radiance.
• Skin Regeneration: Repairs damaged skin barrier and improves texture.
• Cellular Energy: NAD+ boosts ATP production for enhanced cell renewal.
• Anti-Aging: Softens fine lines, improves elasticity, and tightens pores.

Rejuva Healer S is marketed as a 4th Generation Skin Booster. It eliminates the need to layer multiple products by combining the benefits of HA (1st Gen), PDRN (2nd Gen), and Exosomes (3rd Gen) with the added cellular energy boost of NAD+.

What is Rejuva Healer S used for?

Rejuva Healer S is a 4th generation NAD+ skin booster used for deep hydration and glow, skin regeneration and barrier repair, cellular energy boosting, and anti-aging (softening fine lines, improving elasticity, and tightening pores).

What are the key ingredients?

The primary active ingredients are PDRN 2% (Salmon DNA), Hyaluronic Acid 17mg/mL (non-crosslinked), and NAD+ (Nicotinamide Adenine Dinucleotide).

How long do results last?

Hydration and glow are visible immediately after the 1st session, while texture, pore, and elasticity improvements become prominent after the 3rd session. The standard cycle is 3 to 5 sessions spaced 2–3 weeks apart.

Who should administer Rejuva Healer S?

It is for external/professional use only and is administered by injection (papule or nappage technique) using a 30G × 4mm or 32G needle, and should be administered by a qualified professional.

Who manufactures Rejuva Healer S?

Rejuva Healer S is supplied by Phace Global / Esta Global.

Collagenesis-Enabled Solubilized Active and Biodegradable Polymer technology enables PCL to be fully solubilized in water without microparticles, unlike traditional PCL fillers.

GOURI spreads naturally into the surrounding tissue due to its liquid nature and acts as a "Fundamental Anti-Aging" treatment. It biodegrades slowly while stimulating fibroblasts to synthesize new collagen (Neocollagenesis).

• Intense Collagenesis: Stimulation of the skin's natural collagen production.
• Skin Rejuvenation & Lifting: Improvements in skin elasticity, texture, and firmness.
• Wrinkle Reduction: Softens fine lines and deep wrinkles (e.g., crow's feet, marionette lines).
• Natural Volume: Restores volume loss gradually through natural collagen buildup.

Typically requires 2mL (2 syringes) per session for full-face coverage (1mL per side).

Can be safely used for the eye area due to its liquid spreadability.

Mild swelling (edema) is common for 2–3 days post-injection due to the collagenesis inflammatory response. Redness, bruising, or tenderness may occur.

• Avoid heavy makeup for 24 hours.
• Avoid sauna, alcohol, and strenuous exercise for 1 week.

What is GOURI used for?

GOURI is a liquid-type PCL injectable used as a fundamental anti-aging treatment. It stimulates natural collagen production, rejuvenates and lifts skin, softens fine lines and deep wrinkles, and restores natural volume gradually.

What is the key ingredient?

The key ingredient is Polycaprolactone (PCL) at 210mg/mL (21%), delivered as a fully solubilized, microparticle-free liquid using CESABP technology.

How long do results last?

Visual improvements often start within 1–2 weeks, and results typically last 6–12 months as the PCL degrades naturally. The standard cycle is 3 sessions spaced 4 weeks apart, with maintenance of 1–2 sessions every 6–12 months.

Who should administer GOURI?

GOURI is a Class III medical device administered by injection into the deep dermis to subcutaneous layer using a 30G to 35G needle, and should be administered by a qualified medical professional.

Who manufactures GOURI?

GOURI is manufactured by Dexlevo Inc.

• PLLA (Poly-L-Lactic Acid): Derived from Alpha Hydroxy Acid, specifically sourced from plant-based materials like corn and sugarcane.
• CMC (Carboxymethylcellulose): Provides immediate volume upon injection.

Dual-Action Formula: CMC provides instant volume and smoothing upon injection. Over time, PLLA gradually breaks down to stimulate natural collagen regeneration (neocollagenesis). PLLA is completely metabolized by the body into carbon dioxide, water, and simple sugars, leaving no residue behind.

• Immediate plumping and smoothing of the skin via CMC.
• Long-term skin rejuvenation and progressive collagen regeneration via PLLA.
• Restoration of facial and body structure with improved skin elasticity and firmness.

Immediate visible volume from CMC. Natural collagen generation develops over several months, with results lasting up to 2 years.

Typically 24-36 months from the manufacturing date. Single-use vial only; discard any remaining product immediately after use.

• Avoid using the sauna, swimming pool, or gym for at least 7 days after treatment.
• Avoid vigorous facial treatments or massages for 2 weeks post-injection (except for the prescribed 5-5-5 gentle massage).
• Maintain a healthy lifestyle to support optimal collagen production.

It is a collagen biostimulator for immediate plumping and long-term skin rejuvenation, restoring facial and body structure with improved elasticity and firmness.

PLLA (Poly-L-Lactic Acid), a plant-based collagen stimulator sourced from corn and sugarcane, combined with CMC (Carboxymethylcellulose) for immediate volume.

Rejuva Lume is a lyophilized powder and must be reconstituted before use: add Sterile Water for Injection and agitate until a uniform, lump-free suspension forms, following the dilution volume and hydration time in the manufacturer's Instructions for Use.

There is immediate visible volume from CMC, while natural collagen generation develops over several months, with results lasting up to 2 years.

Strictly for professional medical use, injected subcutaneously or into the deep dermis with an 18G cannula or 25-27G needle; do not inject intravascularly.

It is manufactured by Phace Global Co., Ltd.