Anti-aging and Wrinkle Care

Juveheal V uses ICT (Intracellular Transduction) Technology to enhance the penetration of its complex formula into skin cells. It creates an ideal environment for fibroblast activation, regenerating skin components and providing intense hydration for a "Water Glow" effect.

• Radiance & Glow: Instantly improves skin tone and luminosity (Gwangchae).
• Deep Hydration: Restores moisture balance and treats inner dryness with high-dose HA.
• Vitality & Rejuvenation: Revitalizes tired, dull skin and improves overall skin health.
• Barrier Reinforcement: Strengthens the skin's natural defense system.

Full face, specifically for dull, dehydrated, or tired-looking skin.

Remove the flip-off cap and aluminum seal; apply using a dropper or syringe.

Store in a cool, shaded place away from direct sunlight.

• Mild redness or irritation may occur immediately after MTS application but typically subsides within 24 hours.

• Apply a soothing mask and sunscreen.
• Avoid heavy makeup for 24 hours.

What is Juveheal V used for?

Juveheal V is a vitality and radiance ampoule. It improves skin tone and luminosity, provides deep hydration with high-dose HA, revitalizes tired and dull skin, and reinforces the skin barrier for a Water Glow effect.

What are the key ingredients?

The primary active ingredients are High Concentration HA (3,500ppm), Multi-Growth Factors (EGF, FGF, VEGF, IGF), and a Multi-Ingredient Complex of 60+ active ingredients including PDRN.

How is it applied?

It is applied topically and optimized for use with MTS, Derma Pen, or Derma Stamp to facilitate deep absorption. The recommended course is 3 to 5 sessions total, 1 session every 1–2 weeks.

Who should administer Juveheal V?

Juveheal V is for external/cosmetic microneedling use only. For deep absorption it is used with professional devices such as MTS, Derma Pen, or Derma Stamp under professional guidance.

Who manufactures Juveheal V?

Juveheal V is manufactured by J MEDICAL Inter Co., Ltd.

• 1 Surface Smoothing: Botulinum Light Chain Peptide softens fine, superficial lines at the skin surface — without muscle immobilization.
• 2 Structural Renewal: GHK-Cu and PN support the skin's collagen network and promote tissue repair and elasticity restoration.
• 3 Hydration & Radiance: Succinic Acid and HA maintain moisture balance and deliver an even, radiant complexion.

• Softens fine lines and refines overall skin texture
• Supports collagen production and skin regeneration
• Improves hydration and skin radiance

• Avoid intense heat and strenuous exercise for a few days following treatment.

PLLA microparticles stimulate the body's natural collagen production (neocollagenesis) by activating fibroblasts. As the PLLA is gradually absorbed and metabolized by the body, the newly formed collagen restores lost facial volume and improves overall skin elasticity.

Composed of a biodegradable and biocompatible synthetic polymer designed to act as a biostimulator rather than a traditional volumizing filler.

• Gradual and natural-looking volume restoration.
• Deep wrinkle correction.
• Long-term collagen regeneration.
• Improvement of overall skin tone and texture.

Facial contouring, deep wrinkles (e.g., nasolabial folds, marionette lines), sunken cheeks, temples, and jawline.

Results appear gradually over 4 to 6 weeks as new collagen is synthesized. The volumizing and rejuvenating effects are long-lasting, typically persisting for 18 to 24 months.

Store in a cool, dry place away from direct sunlight. Once reconstituted, the product should be used within the recommended timeframe according to standard PLLA protocols.

Patients are typically advised to massage the treated area gently for 5 minutes, 5 times a day, for 5 days to ensure even product distribution and prevent the formation of subcutaneous nodules.

Mild swelling, bruising, redness, and tenderness at the injection sites.

It is a PLLA collagen biostimulator for gradual, natural-looking volume restoration, deep wrinkle correction, and long-term collagen regeneration for facial contouring.

Poly-L-Lactic Acid (PLLA), a biodegradable, biocompatible synthetic polymer that stimulates the body's natural collagen production (neocollagenesis).

It requires proper reconstitution with Sterile Water for Injection (SWFI) prior to the procedure to ensure an even suspension of PLLA particles.

Strictly for professional medical use, via deep dermal or subcutaneous injection; do not inject intravascularly or into the superficial epidermis.

• PLLA: Stimulates natural collagen production from within, enhancing volume and visibly reducing wrinkles over time.
• PN (Polynucleotide / Sodium DNA): Supports skin healing, tissue repair, and cell renewal with high biocompatibility.
• Sodium Hyaluronate: Provides intense moisture, aids regeneration, and reinforces the skin barrier function.
• Glutathione & Vitamin C: Protect against oxidative stress, deliver a brightening effect, and help prevent melanogenesis (melanin production inhibition).

• Optimized particle shape reduces the risk of nodules and granulomas, with a consistent particle size of 30–80 µm to help prevent inflammation.
• Manufactured using advanced preserving technology — formulated without parabens, harsh preservatives, or fragrances.

• Biostimulates collagen production and repairs skin tissue
• Restores volume and deeply hydrates from within
• Brightens complexion and reduces fine lines and acne marks
• Improves overall firmness, skin elasticity, and provides a radiant, youthful glow

• After 1st session: Visible improvements in skin texture, hydration, and brightening.
• After subsequent sessions: Cumulative effects on firmness, fine lines, and collagen restoration.

• 1 Add 4–6 cc of sterilized water to the dry pink powder in the vial.
• 2 Shake thoroughly to ensure even distribution of the powder.
• 3 Leave to set for 2–3 minutes before application.

• Protect from direct sunlight and excessive heat.
• Do not freeze.

• Avoid excessive heat exposure and UV until initial swelling has fully resolved.
• Follow standard post-care protocols for injectable treatments.

• NAD+ (25%): Boosts cellular energy (ATP) and promotes DNA repair for intense skin renewal and vitality.
• PDRN (3%) & PN (1%): Accelerates tissue repair, healing, and skin renewal.
• Plant-derived Exosomes (3 Types): Delivers powerful regenerative signals to support structural repair.
• Atelocollagen (Hydrolyzed): Provides structural support and enhances skin elasticity.

Acts as an advanced multi-booster that reprograms the skin at the cellular level. By enhancing cellular energy (ATP production), it supports faster skin turnover, maximizes collagen synthesis, and delivers deep revitalization.

• Radiance & Glow: Reveals a fresh glow and enhances natural luminosity for a brighter complexion.
• Texture Refinement: Creates a smoother, more refined, and even-looking skin surface.
• Revitalization & Hydration: Provides deep hydration and healthier-looking skin with long-lasting regeneration.

Standard Cycle: 3–5 sessions spaced 1–2 weeks apart.
Onset of Effect: Initial hydration and glow appear within days. Optimal cellular repair and collagen effects become visible after 2–4 weeks.

Because it contains lyophilized exosomes and NAD+, the reconstituted solution must be used immediately and should not be saved or reused.

• Common Effects: Mild redness, swelling, or pinpoint bruising associated with the MTS or injection procedure.
• Post-Care: Apply soothing cream or masks. Strictly avoid direct sun exposure, saunas, and strenuous exercise for at least 24-48 hours. Apply sunscreen diligently.

It is a cellular renewal multi-booster for radiance and glow, texture refinement, and deep revitalization and hydration across the face, neck/décolleté, and hands.

NAD+ (25%), PDRN (3%) & PN (1%), plant-derived exosomes (3 types), and hydrolyzed atelocollagen.

Reconstitute the lyophilized exosome/NAD powder with the provided 6mL solvent, mixing thoroughly until fully dissolved before application; use the reconstituted solution immediately.

Strictly for professional medical/aesthetic use via MTS or intradermal micro-injections; do not inject intravascularly.

• Hyaluronic Acid: Provides intense skin hydration and a sustained moisturizing effect throughout the dermis.
• Glutathione & Coenzymes: Deliver strong antioxidant action and a visible whitening effect by inhibiting melanin production.
• Stem Cells & Exosomes (500 million particles): Exert an excellent effect on skin regeneration and strengthen the skin barrier at a cellular level.
• Amino Acids: Stimulate collagen production to provide firm elasticity and improved skin structure.
• Minerals: Activate cellular metabolism to support overall skin vitality and recovery.

• Revitalizes dull skin and provides deep, lasting hydration
• Strengthens the skin barrier and promotes rapid cell regeneration
• Enhances skin elasticity and firmness
• Delivers strong whitening and antioxidant protection
• Effectively repairs damaged cells and accelerates skin recovery

• Protect from direct sunlight.
• Do not freeze.

• 1 Avoid intense heat sources — saunas and prolonged direct sun exposure — for 24–48 hours post-treatment.
• 2 Avoid strenuous exercise for 24–48 hours post-treatment.

• Barrier Formation: PN forms a physical barrier on the skin to block environmental stressors and maintain optimal moisture levels.
• Fibroblast Activation: Activates fibroblasts to stimulate collagen synthesis, restoring skin structure and elasticity from within.
• Anti-inflammatory Action: Provides anti-inflammatory support to improve the overall skin environment and support tissue recovery.

• Restores oil-water balance and reduces sebum secretion for improved skin texture
• Replenishes elastic fibers including collagen, enhancing the skin's self-healing capacity
• Promotes wound and scar healing
• Effectively improves dryness, pigmentation, wrinkles, and skin sagging

Provides an extended maintenance and retention period attributed to the long DNA chain structure of the PN, which slows degradation and prolongs efficacy in the skin.

• Brightening and whitening — inhibits melanin production for a more even, radiant skin tone
• Deep moisturizing and skin barrier reinforcement
• Wrinkle improvement and skin regeneration
• Strong antioxidant defense against environmental stressors
• General facial brightening, moisturizing, and anti-wrinkle skin conditioning

Apply topically to the facial skin. Effective as a standalone topical treatment — no special MTS (microneedling) procedure is required. Microneedling may optionally be paired for enhanced product absorption at the practitioner's discretion.

• Polynucleotide (PN) 1%: Deeply hydrates the skin, regulates sebum secretion, and softens and brightens skin texture.
• Polydeoxyribonucleotide (PDRN) 1%: Promotes blood circulation, stimulates fibroblast growth to activate collagen and elastin synthesis, and repairs damaged tissues through strong anti-inflammatory effects.

Multi-molecular weight Hyaluronic Acid, Peptide complex, Amino acid blend, and Antioxidants.

Formulated with natural ingredients that have a 97% match to human DNA, effectively preventing allergic and toxic reactions while promoting profound cellular regeneration.

• Intensive Hydration: Restores deep moisture balance.
• Skin Regeneration: Overall skin regeneration, elasticity restoration, and tone enhancement.
• Texture & Clarity: Reduction of fine wrinkles, pore reduction, and alleviation of acne scars.
• Pigmentation: Improvement of melasma and hyperpigmentation.

Microneedling Therapy System (MTS), Mesotherapy (dermal injection), micro-deposit, or grid injection techniques. Efficacy is significantly enhanced when combined with laser treatments or sonophoresis.

Single-use vials. Open and use immediately.

Mild swelling, redness, bruising, and tenderness at the injection site.

• Apply sunscreen diligently.
• Avoid direct sunlight, excessive heat (e.g., saunas), and harsh environments for a few days post-treatment.

It is a cellular skin booster for intensive hydration, skin regeneration and elasticity, fine wrinkle and pore reduction, acne scar improvement, and pigmentation correction.

Polynucleotide (PN) 1% and Polydeoxyribonucleotide (PDRN) 1%, supported by multi-molecular weight Hyaluronic Acid, a peptide complex, amino acids, and antioxidants.

There is immediate hydration and improvement upon administration, with deep cellular regeneration effects lasting up to 12 months, over a course of 3 to 6 sessions at 2 to 4-week intervals.

Strictly for professional medical and aesthetic use via MTS, mesotherapy, micro-deposit, or grid injection; intravascular injection is strictly prohibited.

It is manufactured by Cosmoderma, Inc.

• PDRN (Sodium DNA): Extracted from salmon sperm. Highly compatible with human DNA for cell regeneration.
• Human Adipose-derived Stem Cell Extract: Contains nutrients and growth factors (EGF, FGF, HGF) to produce collagen.
• Hyaluronic Acid: Provides deep moisturization.

Functions as a "New Cell Repairing Factor." The ingredients optimize fibroblastic functions in the dermis, creating an ideal ecosystem to boost core cellular functions and activate tissue regeneration.

• Hydration: +132% improvement in moisture levels.
• Skin Elasticity: +103% improvement in firmness.
• Wrinkle Reduction: +72% reduction in wrinkles and fine lines.
• Tone & Texture: Enhances oil/water balance, softens skin, and provides a whitening effect.

1 Session = 5 Procedures over 3 months.
1st to 3rd Procedure: Spaced 1–2 weeks apart.
4th and 5th Procedure: Spaced 1 month apart (for maintenance).

Discard any remaining product within 7 days after opening due to the lack of preservatives. Keep away from direct sunlight.

• Mild redness, swelling, or pinpoint bleeding temporarily associated with the MTS/injection method. (PDRN is highly compatible with human DNA, minimizing immunological side effects).
• Apply soothing masks or regenerative creams post-procedure.
• Strict sun protection is required to prevent pigmentation during the healing phase.

It is a skin booster for total anti-aging and regeneration, improving hydration, elasticity, wrinkles, and tone on dull, sagging, and wrinkled facial skin.

PDRN (Sodium DNA from salmon sperm), Human Adipose-derived Stem Cell Extract with growth factors, and Hyaluronic Acid, within a composite of 43 active ingredients.

One session is 5 procedures over 3 months: the 1st to 3rd spaced 1–2 weeks apart, and the 4th and 5th spaced 1 month apart for maintenance.

For professional use only, applied via Mesotherapy injection or MTS under strict aseptic conditions since the formula is preservative-free.

• 1 Immediate (CMC Phase): Immediately after injection, the dermis layer is filled with CMC gel, providing instant volume and supporting the surrounding tissue.
• 2 Long-term (PLA Phase): As the CMC gel is gradually absorbed and dissolved, the PLA microspheres remain in place and stimulate cells to produce new collagen — delivering natural wrinkle improvement from the inside out.

• HMT (Homologous Microsphere Technology): Creates perfectly spherical and uniform PLA particles precisely sized at 30–50 µm for consistent, predictable results.
• High Molecular Weight: 190,000–250,000 Da — ensures structural integrity and sustained collagen stimulation over time.
• Eco-Friendly & Biodegradable: No BDDE residue. PLA material fully degrades within 1–2 years.

• Acts as a natural collagen stimulator to dramatically restore volume
• Improves deep wrinkles and gradually rejuvenates overall skin texture
• Delivers dual-phase action: immediate volumizing followed by sustained collagen regeneration

• 1 Add 1.4 mL of WFI (Water For Injection) to the vial.
• 2 Allow to dissolve at room temperature. Standard dissolution time is approximately 1 hour (full dissolution confirmed within 60–90 minutes).
• 3 Confirm beads are completely dissolved before proceeding to injection to ensure even particle suspension.

• Do not freeze.
• Must be properly reconstituted prior to injection to ensure even particle suspension.

The Regenovue series features a monophasic structure manufactured with advanced BDDE cross-linking technology. It offers high viscoelasticity and cohesiveness for smooth, uniform injection. This specific line maintains an exceptionally low endotoxin level (<0.0015 IU/mg) to minimize the risk of inflammation and adverse reactions.