Anti-aging and Wrinkle Care

• PDRN (Sodium DNA): Extracted from salmon sperm. Highly compatible with human DNA for cell regeneration.
• Human Adipose-derived Stem Cell Extract: Contains nutrients and growth factors (EGF, FGF, HGF) to produce collagen.
• Hyaluronic Acid: Provides deep moisturization.

Functions as a "New Cell Repairing Factor." The ingredients optimize fibroblastic functions in the dermis, creating an ideal ecosystem to boost core cellular functions and activate tissue regeneration.

• Hydration: +132% improvement in moisture levels.
• Skin Elasticity: +103% improvement in firmness.
• Wrinkle Reduction: +72% reduction in wrinkles and fine lines.
• Tone & Texture: Enhances oil/water balance, softens skin, and provides a whitening effect.

1 Session = 5 Procedures over 3 months.
1st to 3rd Procedure: Spaced 1–2 weeks apart.
4th and 5th Procedure: Spaced 1 month apart (for maintenance).

Discard any remaining product within 7 days after opening due to the lack of preservatives. Keep away from direct sunlight.

• Mild redness, swelling, or pinpoint bleeding temporarily associated with the MTS/injection method. (PDRN is highly compatible with human DNA, minimizing immunological side effects).
• Apply soothing masks or regenerative creams post-procedure.
• Strict sun protection is required to prevent pigmentation during the healing phase.

It is a skin booster for total anti-aging and regeneration, improving hydration, elasticity, wrinkles, and tone on dull, sagging, and wrinkled facial skin.

PDRN (Sodium DNA from salmon sperm), Human Adipose-derived Stem Cell Extract with growth factors, and Hyaluronic Acid, within a composite of 43 active ingredients.

One session is 5 procedures over 3 months: the 1st to 3rd spaced 1–2 weeks apart, and the 4th and 5th spaced 1 month apart for maintenance.

For professional use only, applied via Mesotherapy injection or MTS under strict aseptic conditions since the formula is preservative-free.

• 1 Immediate (CMC Phase): Immediately after injection, the dermis layer is filled with CMC gel, providing instant volume and supporting the surrounding tissue.
• 2 Long-term (PLA Phase): As the CMC gel is gradually absorbed and dissolved, the PLA microspheres remain in place and stimulate cells to produce new collagen — delivering natural wrinkle improvement from the inside out.

• HMT (Homologous Microsphere Technology): Creates perfectly spherical and uniform PLA particles precisely sized at 30–50 µm for consistent, predictable results.
• High Molecular Weight: 190,000–250,000 Da — ensures structural integrity and sustained collagen stimulation over time.
• Eco-Friendly & Biodegradable: No BDDE residue. PLA material fully degrades within 1–2 years.

• Acts as a natural collagen stimulator to dramatically restore volume
• Improves deep wrinkles and gradually rejuvenates overall skin texture
• Delivers dual-phase action: immediate volumizing followed by sustained collagen regeneration

• 1 Add 1.4 mL of WFI (Water For Injection) to the vial.
• 2 Allow to dissolve at room temperature. Standard dissolution time is approximately 1 hour (full dissolution confirmed within 60–90 minutes).
• 3 Confirm beads are completely dissolved before proceeding to injection to ensure even particle suspension.

• Do not freeze.
• Must be properly reconstituted prior to injection to ensure even particle suspension.

• PLLA: Stimulates natural collagen production from within, enhancing volume and visibly reducing wrinkles over time.
• PN (Polynucleotide / Sodium DNA): Supports skin healing, tissue repair, and cell renewal with high biocompatibility.
• Sodium Hyaluronate: Provides intense moisture, aids regeneration, and reinforces the skin barrier function.
• Glutathione & Vitamin C: Protect against oxidative stress, deliver a brightening effect, and help prevent melanogenesis (melanin production inhibition).

• Optimized particle shape reduces the risk of nodules and granulomas, with a consistent particle size of 30–80 µm to help prevent inflammation.
• Manufactured using advanced preserving technology — formulated without parabens, harsh preservatives, or fragrances.

• Biostimulates collagen production and repairs skin tissue
• Restores volume and deeply hydrates from within
• Brightens complexion and reduces fine lines and acne marks
• Improves overall firmness, skin elasticity, and provides a radiant, youthful glow

• After 1st session: Visible improvements in skin texture, hydration, and brightening.
• After subsequent sessions: Cumulative effects on firmness, fine lines, and collagen restoration.

• 1 Add 4–6 cc of sterilized water to the dry pink powder in the vial.
• 2 Shake thoroughly to ensure even distribution of the powder.
• 3 Leave to set for 2–3 minutes before application.

• Protect from direct sunlight and excessive heat.
• Do not freeze.

• Avoid excessive heat exposure and UV until initial swelling has fully resolved.
• Follow standard post-care protocols for injectable treatments.

PLLA microparticles stimulate the body's natural collagen production (neocollagenesis) by activating fibroblasts. As the PLLA is gradually absorbed and metabolized by the body, the newly formed collagen restores lost facial volume and improves overall skin elasticity.

Composed of a biodegradable and biocompatible synthetic polymer designed to act as a biostimulator rather than a traditional volumizing filler.

• Gradual and natural-looking volume restoration.
• Deep wrinkle correction.
• Long-term collagen regeneration.
• Improvement of overall skin tone and texture.

Facial contouring, deep wrinkles (e.g., nasolabial folds, marionette lines), sunken cheeks, temples, and jawline.

Results appear gradually over 4 to 6 weeks as new collagen is synthesized. The volumizing and rejuvenating effects are long-lasting, typically persisting for 18 to 24 months.

Store in a cool, dry place away from direct sunlight. Once reconstituted, the product should be used within the recommended timeframe according to standard PLLA protocols.

Patients are typically advised to massage the treated area gently for 5 minutes, 5 times a day, for 5 days to ensure even product distribution and prevent the formation of subcutaneous nodules.

Mild swelling, bruising, redness, and tenderness at the injection sites.

It is a PLLA collagen biostimulator for gradual, natural-looking volume restoration, deep wrinkle correction, and long-term collagen regeneration for facial contouring.

Poly-L-Lactic Acid (PLLA), a biodegradable, biocompatible synthetic polymer that stimulates the body's natural collagen production (neocollagenesis).

It requires proper reconstitution with Sterile Water for Injection (SWFI) prior to the procedure to ensure an even suspension of PLLA particles.

Strictly for professional medical use, via deep dermal or subcutaneous injection; do not inject intravascularly or into the superficial epidermis.

Thioctic Acid acts as an antioxidant master, regenerating Vitamin C, E, and Glutathione while scavenging free radicals. It also increases mitochondrial energy expenditure to aid in lipolysis (fat breakdown) and prevents protein glycation to reduce tissue aging.

• Intensive Anti-Aging: Powerful antioxidant protection against cellular damage.
• Skin Brightening: Reduces dullness and improves skin texture ("Baby Face Injection").
• Body Slimming: Boosts metabolism to aid in weight loss and reduce edema.
• Fatigue Recovery: Improves energy levels and exhaustion.
• Diabetic Neuropathy Relief: Relieves sensory abnormalities.

• Nausea, vomiting, or gastrointestinal discomfort (rare with slow drip).
• Skin rash or itching at the injection site.

Avoid heavy alcohol consumption as it interferes with metabolic effects.

High-purity HA attracts water molecules to the dermis, restoring moisture balance immediately while stimulating fibroblasts to promote endogenous collagen synthesis.

• Intensive Moisturizing: Restores dry and dehydrated skin (Hydro-lifting).
• Skin Rejuvenation: Improves overall skin radiance and brightness (Glow effect).
• Texture Improvement: Tightens pores and smoothes fine lines/wrinkles.
• Elasticity Restoration: Enhances skin firmness through collagen stimulation.

Supplied as ready-to-use pre-filled syringes. No mixing required.

Store away from direct sunlight. Do not freeze. Do not use if the package is damaged.

• Mild redness (erythema) or swelling
• Bruising or tenderness at the injection site
• Symptoms usually resolve within 1–3 days

• Avoid heavy makeup for at least 24 hours.
• Avoid saunas, steam rooms, and excessive heat for 1 week.
• Apply sunscreen diligently.

It is used for intensive moisturizing (hydro-lifting), skin rejuvenation and radiance, texture improvement with pore tightening and fine-line smoothing, and elasticity restoration through collagen stimulation.

Its primary active ingredient is Hyaluronic Acid (HA) 15mg/mL (1.5%), buffered with Phosphate Buffered Saline (PBS) pH 7.0.

Visible improvement appears in 1–2 weeks and effects last 3–6 months. A course of 3–4 sessions at 2–3 week intervals is recommended.

It is a medical device for use by licensed practitioners only and should be administered by a qualified professional.

REGENOVUE Aqua Shine is manufactured by NeoGenesis Co., Ltd.

• Brightening and whitening — inhibits melanin production for a more even, radiant skin tone
• Deep moisturizing and skin barrier reinforcement
• Wrinkle improvement and skin regeneration
• Strong antioxidant defense against environmental stressors
• General facial brightening, moisturizing, and anti-wrinkle skin conditioning

Apply topically to the facial skin. Effective as a standalone topical treatment — no special MTS (microneedling) procedure is required. Microneedling may optionally be paired for enhanced product absorption at the practitioner's discretion.

• Hyaluronic Acid: Provides intense skin hydration and a sustained moisturizing effect throughout the dermis.
• Glutathione & Coenzymes: Deliver strong antioxidant action and a visible whitening effect by inhibiting melanin production.
• Stem Cells & Exosomes (500 million particles): Exert an excellent effect on skin regeneration and strengthen the skin barrier at a cellular level.
• Amino Acids: Stimulate collagen production to provide firm elasticity and improved skin structure.
• Minerals: Activate cellular metabolism to support overall skin vitality and recovery.

• Revitalizes dull skin and provides deep, lasting hydration
• Strengthens the skin barrier and promotes rapid cell regeneration
• Enhances skin elasticity and firmness
• Delivers strong whitening and antioxidant protection
• Effectively repairs damaged cells and accelerates skin recovery

• Protect from direct sunlight.
• Do not freeze.

• 1 Avoid intense heat sources — saunas and prolonged direct sun exposure — for 24–48 hours post-treatment.
• 2 Avoid strenuous exercise for 24–48 hours post-treatment.

• Barrier Formation: PN forms a physical barrier on the skin to block environmental stressors and maintain optimal moisture levels.
• Fibroblast Activation: Activates fibroblasts to stimulate collagen synthesis, restoring skin structure and elasticity from within.
• Anti-inflammatory Action: Provides anti-inflammatory support to improve the overall skin environment and support tissue recovery.

• Restores oil-water balance and reduces sebum secretion for improved skin texture
• Replenishes elastic fibers including collagen, enhancing the skin's self-healing capacity
• Promotes wound and scar healing
• Effectively improves dryness, pigmentation, wrinkles, and skin sagging

Provides an extended maintenance and retention period attributed to the long DNA chain structure of the PN, which slows degradation and prolongs efficacy in the skin.

• Polynucleotide (PN) 1%: Deeply hydrates the skin, regulates sebum secretion, and softens and brightens skin texture.
• Polydeoxyribonucleotide (PDRN) 1%: Promotes blood circulation, stimulates fibroblast growth to activate collagen and elastin synthesis, and repairs damaged tissues through strong anti-inflammatory effects.

Multi-molecular weight Hyaluronic Acid, Peptide complex, Amino acid blend, and Antioxidants.

Formulated with natural ingredients that have a 97% match to human DNA, effectively preventing allergic and toxic reactions while promoting profound cellular regeneration.

• Intensive Hydration: Restores deep moisture balance.
• Skin Regeneration: Overall skin regeneration, elasticity restoration, and tone enhancement.
• Texture & Clarity: Reduction of fine wrinkles, pore reduction, and alleviation of acne scars.
• Pigmentation: Improvement of melasma and hyperpigmentation.

Microneedling Therapy System (MTS), Mesotherapy (dermal injection), micro-deposit, or grid injection techniques. Efficacy is significantly enhanced when combined with laser treatments or sonophoresis.

Single-use vials. Open and use immediately.

Mild swelling, redness, bruising, and tenderness at the injection site.

• Apply sunscreen diligently.
• Avoid direct sunlight, excessive heat (e.g., saunas), and harsh environments for a few days post-treatment.

It is a cellular skin booster for intensive hydration, skin regeneration and elasticity, fine wrinkle and pore reduction, acne scar improvement, and pigmentation correction.

Polynucleotide (PN) 1% and Polydeoxyribonucleotide (PDRN) 1%, supported by multi-molecular weight Hyaluronic Acid, a peptide complex, amino acids, and antioxidants.

There is immediate hydration and improvement upon administration, with deep cellular regeneration effects lasting up to 12 months, over a course of 3 to 6 sessions at 2 to 4-week intervals.

Strictly for professional medical and aesthetic use via MTS, mesotherapy, micro-deposit, or grid injection; intravascular injection is strictly prohibited.

It is manufactured by Cosmoderma, Inc.

• H-HA (High molecular weight HA): 67.5mg
• L-HA (Low molecular weight HA): 67.5mg
• PDRN (Polydeoxyribonucleotide): 5mg
• PN (Polynucleotide): 5mg

H-HA & L-HA provide intense moisture, enhance skin elasticity, and maintain long-lasting volume. PDRN & PN promote cell regeneration, offer anti-inflammatory effects, enhance wound healing, and repair broken collagen and elastin fibers.

• Hydration & Volume: Intense moisturizing and long-lasting volume support.
• Rejuvenation: Wrinkle reduction, collagen & elastin regeneration.
• Healing & Tone: Anti-inflammatory wound healing, whitening, and scar/acne improvement.

Cycle: 3 treatments at 2-week intervals.
Onset: Rapid onset with PDRN/PN action visible in 1-2 weeks.
Duration: Overall effect lasts 4 to 8 months.

Single-use vial. Discard any remaining solution after opening.

• Common Effects: Mild swelling, redness, bruising, tenderness, or temporary papules (bumps) at injection sites.
• Post-Care: Avoid heavy makeup for 24 hours. Avoid extreme heat (saunas, hot baths) and strenuous exercise for a few days. Apply sunscreen regularly.

It is a skin booster for deep hydration, skin texture improvement, wrinkle reduction, wound healing, and overall cell regeneration across the full face, neck, and back of hand.

A complex of H-HA and L-HA (67.5mg each) plus PDRN (5mg) and PN (5mg) per 5mL, combining HA hydration with PDRN/PN cell regeneration.

The overall effect lasts 4 to 8 months, with PDRN/PN action visible in 1-2 weeks, following a cycle of 3 treatments at 2-week intervals.

It is strictly for professional medical use and must not be injected intravascularly.

It is manufactured by Healink Korea.

The Regenovue series features a monophasic structure manufactured with advanced BDDE cross-linking technology. It offers high viscoelasticity and cohesiveness for smooth, uniform injection. This specific line maintains an exceptionally low endotoxin level (<0.0015 IU/mg) to minimize the risk of inflammation and adverse reactions.

The Wellsfil series features a monophasic gel structure designed to provide smooth injection, uniform tissue integration, and structural stability. The series includes 0.3% lidocaine to minimize patient discomfort during the procedure. It is available in three viscoelastic variants to target different depths of the skin and address various aesthetic concerns, from superficial wrinkles to deep facial contouring.