Fiola PLLA Hybrid Biostimulator
Fiola PLLA by Medi-Fella: a hybrid collagen biostimulator combining Poly-L-Lactic Acid (PLLA) with CMC and hyaluronic acid, in 50mg, 200mg, 400mg and 1000mg tiers.
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Fiola PLLA (50mg / 200mg / 400mg / 1000mg)
From $88.00
Unit price perFiola PLLA (50mg / 200mg / 400mg / 1000mg)
From $88.00
Unit price per
Fiola PLLA
A hybrid collagen-stimulating filler series combining PLLA (Poly-L-lactic acid) with CMC (Carboxymethylcellulose) and HA (Hyaluronic Acid). Once injected, PLLA gradually degrades into lactic acid, stimulating fibroblasts to secrete Type III collagen — progressively remodeled into Type I collagen — to rebuild the skin's collagen network over time. CMC ensures even dispersion of PLLA microspheres and supports collagen production. HA provides fast hydration and elasticity from the first session.
- Patented smooth-surface PLLA microspheres — reduces aggregation, nodules, and embolism risk
- Particle size above 20 µm — prevents phagocytosis by immune cells
- Freeze-drying technology — moisture residue under 0.5% for long-term stability
- Fast full hydration — 15–30 minutes (vs. 8–24 hours for many competing PLLA products)
- Low injection force — 0.9–2.0 N with a 26G needle
| Feature | 50mg Soft | 200mg Mid | 400mg Hard | 1000mg Extra |
|---|---|---|---|---|
| Composition | 42.5mg PLLA + 7.5mg HA & CMC | 170mg PLLA + 30mg HA & CMC | 340mg PLLA + 60mg HA & CMC | 850mg PLLA + 150mg HA & CMC |
| Particle Size | ~30 µm | ~50 µm | ~50 µm | 80–120 µm |
| Injection Layer | Intradermal, Dermis | Dermis, Subcutaneous | Dermis, Subcutaneous | Subcutaneous |
| Reconstitution | 0.75mL saline + 0.3mL lidocaine | 4mL saline + 1mL lidocaine | 6–10mL saline + 2–3mL lidocaine | 15mL saline + 5mL 2% lidocaine (20mL total) |
| Primary Use | Fine wrinkles, pores, tear trough, skin rejuvenation | Deep wrinkles, facial contouring | Deep scars, stretch marks, breast/buttock mid-volume | Buttocks, breasts, calves, cellulite, male girth enhancement |
| Duration | 1–2 years | 2–3 years | 2–3 years | 2–5 years |
| Pack Size | 50mg × 10ea / box | 200mg × 10ea / box | 400mg × 10ea / box | 1000mg × 1 vial × 10ea / box |
- Store at room temperature, below 30°C · Protect from direct light · Do not freeze
- After reconstitution: usable at room temperature (up to 30°C) for up to 72 hours, or refrigerated for up to 14 days
Fiola PLLA 50mg — Soft Stimulator
Entry-level "Soft Stimulator" — lowest PLLA concentration and smallest particle size in the line, optimized for superficial skin-quality improvement rather than structural volumizing.
Fiola PLLA 200mg — Mid Stimulator
Mid-tier version for deep-layer facial injection — bridges the superficial 50mg and structural 400mg tiers for deeper tissue structure support.
Fiola PLLA 400mg — Hard Stimulator
Higher-concentration tier for deeper body injections — bridges the facial-focused 200mg and the full-body-volumizing 1000mg Extra tiers.
Fiola PLLA 1000mg — Extra Stimulator
Top-tier, largest-particle version designed exclusively for deep-body volumizing applications. Distinct dilution and hydration protocol compared to other variants — requires a 30–40 minute hydration rest after reconstitution.
| Treatment Area | Vials / Session | Notes |
|---|---|---|
| Buttocks & Hips | 3–4 vials | Hyper-diluted (20 mL+) · fanned into subcutaneous tissue |
| Breasts | 3–4 vials | High-volume dilution into deep subcutaneous layer — avoid glandular tissue |
| Calves | 1–2 vials per calf | Deep subcutaneous / fascial layer |
| Penile Girth | Per protocol | Non-incisional · local anesthesia · ~10 min procedure · no suture removal required · 21–23G blunt cannula |