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Fiola PLLA (50mg / 200mg / 400mg / 1000mg)

$88.00

Option

Formulation

Key ingredients

  • 01 Poly-L-Lactic Acid (PLLA)85% of vial weight (42.5 mg in 50mg vial)Biodegradable microspheres used as a gradual collagen biostimulator.
  • 02 Carboxymethyl Cellulose (CMC)15% of vial weight, combined with HASuspending agent that helps disperse the PLLA microspheres evenly.
  • 03 Hyaluronic Acid15% of vial weight, combined with CMCHydrating component of the hybrid formulation.

Product Line Overview
Medi-Fella Ltd. · Seoul, Korea PLLA Collagen Stimulator

Fiola PLLA

50mg Soft / 200mg Mid / 400mg Hard / 1000mg Extra

A hybrid collagen-stimulating filler series combining PLLA (Poly-L-lactic acid) with CMC (Carboxymethylcellulose) and HA (Hyaluronic Acid). Once injected, PLLA gradually degrades into lactic acid, stimulating fibroblasts to secrete Type III collagen — progressively remodeled into Type I collagen — to rebuild the skin's collagen network over time. CMC ensures even dispersion of PLLA microspheres and supports collagen production. HA provides fast hydration and elasticity from the first session.

Common Technologies Across All Variants
  • Patented smooth-surface PLLA microspheres — reduces aggregation, nodules, and embolism risk
  • Particle size above 20 µm — prevents phagocytosis by immune cells
  • Freeze-drying technology — moisture residue under 0.5% for long-term stability
  • Fast full hydration — 15–30 minutes (vs. 8–24 hours for many competing PLLA products)
  • Low injection force — 0.9–2.0 N with a 26G needle
PLLA + CMC + HA Hybrid Smooth-Surface Microspheres Freeze-Dried · <0.5% Moisture 26G Needle Compatible ISO 9001 · ISO 14001 · GMP Korean Venture Certified
Quick Version Comparison
Feature 50mg Soft 200mg Mid 400mg Hard 1000mg Extra
Composition 42.5mg PLLA + 7.5mg HA & CMC 170mg PLLA + 30mg HA & CMC 340mg PLLA + 60mg HA & CMC 850mg PLLA + 150mg HA & CMC
Particle Size ~30 µm ~50 µm ~50 µm 80–120 µm
Injection Layer Intradermal, Dermis Dermis, Subcutaneous Dermis, Subcutaneous Subcutaneous
Reconstitution 0.75mL saline + 0.3mL lidocaine 4mL saline + 1mL lidocaine 6–10mL saline + 2–3mL lidocaine 15mL saline + 5mL 2% lidocaine (20mL total)
Primary Use Fine wrinkles, pores, tear trough, skin rejuvenation Deep wrinkles, facial contouring Deep scars, stretch marks, breast/buttock mid-volume Buttocks, breasts, calves, cellulite, male girth enhancement
Duration 1–2 years 2–3 years 2–3 years 2–5 years
Pack Size 50mg × 10ea / box 200mg × 10ea / box 400mg × 10ea / box 1000mg × 1 vial × 10ea / box
Common Storage, Handling & Precautions
Storage (All Variants)
  • Store at room temperature, below 30°C · Protect from direct light · Do not freeze
  • After reconstitution: usable at room temperature (up to 30°C) for up to 72 hours, or refrigerated for up to 14 days
Common Contraindications — All Variants Contraindicated during pregnancy, breastfeeding, and in children. Do not inject into areas with chronic skin disease or around active inflammation/infection. Not suitable for the thin skin of the lip vermilion border. Avoid excessive sun exposure at the injection site post-treatment to prevent hyperpigmentation.

Product Identification

Fiola PLLA 50mg — Soft Stimulator

Intradermal / Dermis ~30 µm Particle
Composition
42.5mg PLLA + 7.5mg HA & CMC · 50mg/vial × 10ea per box
Version Role

Entry-level "Soft Stimulator" — lowest PLLA concentration and smallest particle size in the line, optimized for superficial skin-quality improvement rather than structural volumizing.

Efficacy & Targeted Areas
Main Effects
Fine wrinkles, skin rejuvenation/booster effect, acne scar improvement, pore reduction, tear trough correction
Treatment Areas
Facial Skin Texture Tear Trough Neck Fine Wrinkles Acne Scars Large Pores
Duration of Effect
1–2 years
Application Guide
Injection Method
Intradermal / Dermal injection · 26G needle
Volume per Point
0.1–0.2 mL per direct-injection point · 0.02–0.05 mL per point if using MTS / meso-injector
Reconstitution
0.75 mL normal saline → add 0.3 mL lidocaine before injection (optional)
Collagen Peak Onset
Collagen production typically peaks around 30 days post-injection

Product Identification

Fiola PLLA 200mg — Mid Stimulator

Dermis / Subcutaneous ~50 µm Particle
Composition
170mg PLLA + 30mg HA & CMC · 200mg/vial × 10ea per box
Version Role

Mid-tier version for deep-layer facial injection — bridges the superficial 50mg and structural 400mg tiers for deeper tissue structure support.

Efficacy & Targeted Areas
Main Effects
Deep wrinkle correction, facial contouring, acne/deep scar improvement
Treatment Areas
Nasolabial Folds Marionette Lines Neck Forehead Temples Cheeks Chin Deep Acne Scars
Duration of Effect
2–3 years
Application Guide
Injection Method
Dermal to subcutaneous injection · 26G needle
Reconstitution
4 mL normal saline → add 1 mL lidocaine before injection

Product Identification

Fiola PLLA 400mg — Hard Stimulator

Dermis / Subcutaneous ~50 µm Particle
Composition
340mg PLLA + 60mg HA & CMC · 400mg/vial × 10ea per box
Version Role

Higher-concentration tier for deeper body injections — bridges the facial-focused 200mg and the full-body-volumizing 1000mg Extra tiers.

Efficacy & Targeted Areas
Main Effects
Deep body injections for stretch marks, hand/neck wrinkles, mid-volume breast/buttock enhancement
Treatment Areas
Stretch Marks Hand Wrinkles Neck Wrinkles Breast — Mid-Volume Buttock — Mid-Volume
Duration of Effect
2–3 years
Application Guide
Injection Method
Dermal to subcutaneous injection · 26G needle
Reconstitution
6–10 mL normal saline → add 2–3 mL lidocaine
Breast / Buttock Protocol
1 vial + 10 mL saline · typically 7–10 vials per session (per manufacturer's area guide)

Product Identification

Fiola PLLA 1000mg — Extra Stimulator

Subcutaneous 80–120 µm Particle
Composition
850mg PLLA + 150mg HA & CMC · 1000mg × 1 vial × 10ea per box
Version Role

Top-tier, largest-particle version designed exclusively for deep-body volumizing applications. Distinct dilution and hydration protocol compared to other variants — requires a 30–40 minute hydration rest after reconstitution.

Efficacy & Targeted Areas
Main Effects
Significant volume addition and structural support for large body areas and cellulite smoothing
Treatment Areas
Buttocks / Hip Dips Breast Volumizing Calf Contouring Cellulite Smoothing Penile Girth Enhancement
Duration of Effect
2–5 years
Application Guide
Injection Method
Subcutaneous injection · 26G needle (standard) · 21–23G blunt cannula for male girth enhancement application
Reconstitution & Hydration
15 mL normal saline + 5 mL 2% lidocaine = 20 mL total per vial · Rest 30–40 minutes for full hydration before use · Mix to uniform translucent suspension before drawing into syringes
Protocol by Area
Treatment Area Vials / Session Notes
Buttocks & Hips 3–4 vials Hyper-diluted (20 mL+) · fanned into subcutaneous tissue
Breasts 3–4 vials High-volume dilution into deep subcutaneous layer — avoid glandular tissue
Calves 1–2 vials per calf Deep subcutaneous / fascial layer
Penile Girth Per protocol Non-incisional · local anesthesia · ~10 min procedure · no suture removal required · 21–23G blunt cannula
Clinical Tip — Large Body Areas For large body areas, practitioners may further increase saline dilution to 30–40 mL+ per vial to improve particle dispersion and reduce nodule risk.
Professional Expertise Required Large-volume body and genital applications must only be performed by practitioners with specific experience in these advanced techniques.
Keywords & Search Terms
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Authentic Fiola PLLA Soft Mid Hard Extra PLLA HA CMC Collagen Biostimulator Skin Rejuvenation Body Volumizing Korea Wholesale

Fiola PLLA (50mg / 200mg / 400mg / 1000mg)

$88.00

$88.00

Further reading