Skin Boosters and Ampoules

• A2A Receptor Activation: PDRN binds to adenosine A2A receptors to exert anti-inflammatory effects and repair damaged tissues.
• Salvage Pathway: Provides nucleosides (DNA precursors) via the salvage pathway to promote rapid DNA synthesis and cell proliferation.
• Growth Factor Stimulation: Promotes the secretion of VEGF and other growth factors to aid angiogenesis and wound healing.

• Tissue Regeneration: Repairs damaged skin barrier, improves skin thickness, and treats ligament/tendon injuries.
• Pore & Scar Reduction: Diminishes acne scars and tightens pores.
• Rapid Healing: Accelerates wound healing and provides anti-inflammatory support.
• Texture Improvement: Enhances overall skin texture and hydration.

• Medical (Systemic/Local): Intramuscular (IM) or Subcutaneous (SC) injection.
• Aesthetic (Off-label): Intradermal (ID) injection (Mesotherapy) or MTS (Microneedling) application to the face.

• Mild pain, redness, or swelling at the injection site.
• Bruising from the needle insertion.

What is Rejuvenex Forte used for?

Rejuvenex Forte is a high-concentration PDRN solution used for tissue regeneration, pore and scar reduction, rapid wound healing with anti-inflammatory support, and overall skin texture improvement.

What is the key ingredient?

The primary active ingredient is Polydeoxyribonucleotide Sodium (PDRN) at 14.06mg per 2.5mL, derived from salmon DNA.

How long do results last?

Visible skin improvements are often noted after 3–4 sessions, and tissue regeneration effects are cumulative. The typical course is 1 session per week for 3–5 weeks.

Who should administer Rejuvenex Forte?

It is an ethical drug (ETC) administered by injection, including intramuscular or subcutaneous injection and aesthetic intradermal (mesotherapy) or MTS application, and should be administered by a qualified medical professional.

Who manufactures Rejuvenex Forte?

Rejuvenex Forte is manufactured by PharmaResearch Co., Ltd.

• c-PDRN (Cosmetic Polydeoxyribonucleotide): Hydrolyzed DNA from salmon, optimized for skin absorption to repair damaged cells.
• Sodium Hyaluronate (HA): High-quality European hyaluronic acid for intense hydration.

A Double Effect system where HA provides immediate deep hydration and volume support, while c-PDRN penetrates the barrier to stimulate biological regeneration and collagen synthesis.

• Deep Hydration (Hydro-Lifting): Relieves inner skin dryness and provides a radiant "water glow."
• Skin Regeneration: Repairs skin barrier damaged by external irritation or aesthetic procedures (e.g., lasers).
• Texture Improvement: Softens rough skin texture and improves elasticity.
• Soothing: Calms sensitive and tired skin.

Apply to cleansed skin. Highly recommended for use with aesthetic devices such as MTS (Microneedling), Electroporation, or Iontophoresis to enhance penetration.

• Intensive Care: 3–5 sessions at 1–2 week intervals.
• Maintenance: 1 session every 1–2 months.

Mild redness or irritation may occur if used with aggressive MTS, usually subsiding within 24 hours.

What is Rejuvenex Hydro Essence used for?

Rejuvenex Hydro Essence is a hydro-lifting skin booster used for deep hydration and a radiant water glow, skin barrier regeneration (including post-procedure repair), texture improvement, and soothing sensitive or tired skin.

What are the key ingredients?

The primary active ingredients are c-PDRN (Cosmetic Polydeoxyribonucleotide, hydrolyzed salmon DNA) and Sodium Hyaluronate (Hyaluronic Acid).

How is it applied?

It comes in a ready-to-use pre-filled syringe and is applied to cleansed skin. It is highly recommended for use with aesthetic devices such as MTS (Microneedling), Electroporation, or Iontophoresis. Intensive care is 3–5 sessions at 1–2 week intervals.

Who should administer Rejuvenex Hydro Essence?

It is for external (topical) use only. When combined with aesthetic devices such as MTS, Electroporation, or Iontophoresis, it should be used under professional guidance.

Who manufactures Rejuvenex Hydro Essence?

Rejuvenex Hydro Essence is manufactured by PharmaResearch Co., Ltd.

Polynucleotide (derived from salmon DNA) regenerates tissue and improves skin density in the dermis, while Hyaluronic Acid provides deep hydration. Glutathione acts as an antioxidant to brighten the skin, and Collagen Peptides stimulate elasticity.

Targeted eye rejuvenation including dark circle reduction and brightening. It provides fine wrinkle correction (Crow's feet), strengthens the skin barrier, and offers deep hydration with improved elasticity.

Under-eye area (Tear troughs), Crow's feet, Neckline, Back of hands, and thin wrinkles on the face.

Ready-to-use pre-filled syringe (No reconstitution required).

Store away from direct sunlight. The product is for single-use only.

• Temporary redness at the injection site
• Swelling or bruising
• Tenderness

• Avoid heavy makeup for a few hours post-injection
• Avoid touching the treated area

It is used for targeted eye rejuvenation, including dark circle reduction, brightening, fine wrinkle correction (Crow's feet), skin barrier strengthening, and deep hydration with improved elasticity.

Its primary active ingredients are Polynucleotide (PN) 1% (derived from salmon DNA) and Sodium Hyaluronate (HA) 0.5%.

It is administered by injection (mesotherapy / intradermal injection) using a 32G or 33G (4mm length) needle, with 3 sessions recommended at 20–30 day intervals.

It is for professional use only and should be administered by a qualified practitioner.

REJUBEAU Eye Deal is manufactured by TRACLE INC.

• Hyaluronic Acid (HA): 64mg/2mL (32mg High MW + 32mg Low MW)
• Succinic Acid: 16mg (1.6%) – Antioxidant & Anti-inflammatory
• Peptide Complex: Tripeptide-29 (Collagen Type I stimulation)

This high-concentration HA formula acts as a scaffold for immediate deep hydration (Bio-remodeling). Simultaneously, Succinic Acid activates mitochondrial energy to reduce inflammation, while Tripeptide-29 specifically targets collagen upregulation to restore elasticity.

• Deep Hydration & Glow: Restores moisture balance in dehydrated skin.
• Lifting & Tightening: Improves skin laxity via bio-remodeling.
• Anti-Inflammatory: Succinic Acid reduces redness, suitable for sensitive skin.
• Wrinkle Reduction: Smoothes fine lines and improves texture.

Ready-to-use pre-filled syringe; no mixing required.

EVEHILO is positioned as an advanced bio-remodeler alternative to products like Profhilo. It differentiates itself by incorporating Succinic Acid for brightening and anti-inflammatory benefits, alongside Tripeptide-29 for enhanced collagen stimulation.

Best for patients requiring both structural lifting/tightening and skin quality improvement (treating acne scars, pigmentation, or dullness).

Store in a cool, dry place away from direct sunlight. Do not freeze. Single-use only.

• Mild redness, swelling, or localized bumps (papules) at injection points (usually resolve within 24–48 hours).
• Bruising may occur.

• Avoid heavy makeup for 12 hours.
• Avoid saunas, steam rooms, and intense exercise for a few days.

It is used for deep hydration and glow, lifting and tightening via bio-remodeling, anti-inflammatory benefits for sensitive skin, and wrinkle reduction with texture improvement.

Its primary active ingredients are Hyaluronic Acid (HA) 64mg/2mL (32mg High MW + 32mg Low MW), Succinic Acid 16mg (1.6%), and a peptide complex featuring Tripeptide-29.

Visible improvement appears in 1–2 weeks and effects last 6–9 months. An initial course of 2 treatments spaced 4 weeks apart is recommended.

It is for professional use only and should be administered by a qualified practitioner.

EVEHILO is associated with Celesta Korea / BS Pharm.

Polynucleotide (PN), derived from salmon DNA, acts as a tissue regeneration activator. It stimulates the synthesis of collagen and elastin in the dermis (Extra Cellular Matrix restoration) and promotes angiogenesis (formation of new blood vessels) to improve skin density and thickness.

Provides comprehensive skin regeneration and wound healing by accelerating the repair of damaged skin. It improves elasticity and reduces fine lines for anti-aging, smooths skin texture while reducing pore size, and strengthens the skin barrier against environmental stress.

Full Face (General skin rejuvenation), Neck wrinkles, areas with acne scars or enlarged pores, and thin/damaged skin requiring regeneration.

Ready-to-use pre-filled syringe. No dilution required.

Store away from direct sunlight. Do not freeze. Single-use only; discard any remaining solution.

• "Embossing" (small raised bumps) - typically subsides within 24–48 hours
• Mild redness (Erythema), swelling, or bruising
• Mild pain or tenderness

• Avoid makeup for at least 6–12 hours
• Avoid saunas, steam rooms, heavy exercise, and alcohol for 3–7 days
• Apply sunscreen and moisturizer regularly

It provides comprehensive skin regeneration and wound healing, improving elasticity, reducing fine lines for anti-aging, smoothing skin texture while reducing pore size, and strengthening the skin barrier.

Its primary active ingredient is Polynucleotide (PN) 2% (20mg/ml), derived from salmon DNA.

Visible improvements typically appear 1–2 weeks after the first session, with effects lasting 6–12 months. A course of 3 to 4 sessions at 2–3 week intervals is recommended.

It is for professional use only and should be administered by licensed medical practitioners.

REJUBEAU PN Healer is manufactured by TRACLE INC.

Tranexamoyl Dipeptide-23, Glutathione, Vitamin C, Arbutin, Niacinamide, and Sodium DNA.

Peptides (Tetrapeptide, Oligopeptide-2/IGF-1, Polypeptide-1/bFGF), N-Acetyl Glucosamine, and Pantothenic Acid (Vitamin B5).

The active components block the action of tyrosinase (the enzyme responsible for melanin formation) to effectively reduce melanin production. The formula actively integrates with cellular metabolism to deliver progressive multi-step whitening from the surface to the deeper epidermal layer, while peptides and vitamins stimulate skin regeneration and elasticity.

Exceptional biocompatibility that is free from cytotoxic effects. It features a stable formulation that minimizes irritation and provides powerful antioxidant defense against environmental damage.

• Intensive skin whitening and brightening.
• Reduction of deep-rooted pigmentation and dark spots.
• Improvement of skin elasticity and texture.
• Pore size reduction and overall anti-aging rejuvenation.

• Face: 1.5–2.0mL
• Neck: 1.0–1.5mL
• Décolletage: 2.0–2.5mL
• Hands: 2.0–3.0mL

Cycle: Standard mesotherapy protocols generally recommend 3–5 sessions at 1–2 week intervals.
Duration: Progressively achieves deeper, more pronounced lightening over time. The anti-aging and brightening benefits are long-lasting, with effects persisting for up to 9 months.

Keep away from direct sunlight and excessive heat. Intended for professional use; strictly discard any remaining solution after opening a vial.

Mild redness, swelling, or pinpoint bruising associated with the injection or microneedling procedure.

• Apply sunscreen diligently to protect the treated areas and prevent UV-induced pigmentation.
• Avoid direct sunlight, saunas, and harsh environments for a few days post-treatment.

It is a whitening and pigmentation mesotherapy solution for intensive skin brightening, reducing deep-rooted pigmentation and dark spots, and improving skin elasticity and texture.

Tranexamoyl Dipeptide-23, Glutathione, Vitamin C, Arbutin, Niacinamide, and Sodium DNA, which inhibit tyrosinase to reduce melanin production.

Over a course of 3–5 sessions at 1–2 week intervals, the anti-aging and brightening benefits are long-lasting, with effects persisting for up to 9 months.

Intended for use by certified cosmetologists and medical professionals only, via mesotherapy injection or MTS; intravascular injection is strictly prohibited.

It is manufactured by Cosmoderma Inc.

• NAD+ (25%): Boosts cellular energy (ATP) and promotes DNA repair for intense skin renewal and vitality.
• PDRN (3%) & PN (1%): Accelerates tissue repair, healing, and skin renewal.
• Plant-derived Exosomes (3 Types): Delivers powerful regenerative signals to support structural repair.
• Atelocollagen (Hydrolyzed): Provides structural support and enhances skin elasticity.

Acts as an advanced multi-booster that reprograms the skin at the cellular level. By enhancing cellular energy (ATP production), it supports faster skin turnover, maximizes collagen synthesis, and delivers deep revitalization.

• Radiance & Glow: Reveals a fresh glow and enhances natural luminosity for a brighter complexion.
• Texture Refinement: Creates a smoother, more refined, and even-looking skin surface.
• Revitalization & Hydration: Provides deep hydration and healthier-looking skin with long-lasting regeneration.

Standard Cycle: 3–5 sessions spaced 1–2 weeks apart.
Onset of Effect: Initial hydration and glow appear within days. Optimal cellular repair and collagen effects become visible after 2–4 weeks.

Because it contains lyophilized exosomes and NAD+, the reconstituted solution must be used immediately and should not be saved or reused.

• Common Effects: Mild redness, swelling, or pinpoint bruising associated with the MTS or injection procedure.
• Post-Care: Apply soothing cream or masks. Strictly avoid direct sun exposure, saunas, and strenuous exercise for at least 24-48 hours. Apply sunscreen diligently.

It is a cellular renewal multi-booster for radiance and glow, texture refinement, and deep revitalization and hydration across the face, neck/décolleté, and hands.

NAD+ (25%), PDRN (3%) & PN (1%), plant-derived exosomes (3 types), and hydrolyzed atelocollagen.

Reconstitute the lyophilized exosome/NAD powder with the provided 6mL solvent, mixing thoroughly until fully dissolved before application; use the reconstituted solution immediately.

Strictly for professional medical/aesthetic use via MTS or intradermal micro-injections; do not inject intravascularly.

A synergistic effect of Hydration (HA), Regeneration (PDRN), and Cellular Recharging (NAD+). It acts as a bio-stimulator to activate the skin's natural healing and energy production cycles.

• Deep Hydration & Glow: Provides an instant moisture boost and "water glow" radiance.
• Skin Regeneration: Repairs damaged skin barrier and improves texture.
• Cellular Energy: NAD+ boosts ATP production for enhanced cell renewal.
• Anti-Aging: Softens fine lines, improves elasticity, and tightens pores.

Rejuva Healer S is marketed as a 4th Generation Skin Booster. It eliminates the need to layer multiple products by combining the benefits of HA (1st Gen), PDRN (2nd Gen), and Exosomes (3rd Gen) with the added cellular energy boost of NAD+.

What is Rejuva Healer S used for?

Rejuva Healer S is a 4th generation NAD+ skin booster used for deep hydration and glow, skin regeneration and barrier repair, cellular energy boosting, and anti-aging (softening fine lines, improving elasticity, and tightening pores).

What are the key ingredients?

The primary active ingredients are PDRN 2% (Salmon DNA), Hyaluronic Acid 17mg/mL (non-crosslinked), and NAD+ (Nicotinamide Adenine Dinucleotide).

How long do results last?

Hydration and glow are visible immediately after the 1st session, while texture, pore, and elasticity improvements become prominent after the 3rd session. The standard cycle is 3 to 5 sessions spaced 2–3 weeks apart.

Who should administer Rejuva Healer S?

It is for external/professional use only and is administered by injection (papule or nappage technique) using a 30G × 4mm or 32G needle, and should be administered by a qualified professional.

Who manufactures Rejuva Healer S?

Rejuva Healer S is supplied by Phace Global / Esta Global.

• High molecular weight HA: 67.5mg
• Low molecular weight HA: 67.5mg
• Polydeoxyribonucleotide (PDRN): 5.0mg
• Polynucleotide (PN): 5.0mg

Cellular Rejuvenation: PDRN and PN (derived from salmon DNA) repair broken collagen and elastin fibers, stimulate fibroblasts to generate new tissue, normalize fibroblast size, and provide anti-inflammatory and wound-healing effects. Dual Hydration: H-HA and L-HA synergistically provide deep and surface hydration, enhance elasticity, and maintain volume.

• Intense Under-Eye Rejuvenation: Specifically targeted treatment for the delicate eye area.
• Deep Hydration & Volume: Replenishes moisture and restores sagging, hollow areas.
• Fine Lines & Wrinkles: Softens and reduces the appearance of wrinkles, including crow's feet.
• Regeneration & Calming: Repairs damaged tissue, improves elasticity, and provides anti-inflammatory healing.

Typically 24–36 months from the manufacturing date (Unopened). Single-use only. Discard any remaining product.

Mild swelling, bruising, redness, tenderness, or temporary papules (small bumps) at the injection sites.

It is a skin booster for intense under-eye rejuvenation, treating tear troughs, crow's feet, under-eye hollows, and eyelids with deep hydration and wrinkle reduction.

High and low molecular weight HA (67.5mg each) plus PDRN (5.0mg) and PN (5.0mg) derived from salmon DNA.

Significant visible improvements, including deep hydration and wrinkle reduction, are typically noted prominently around 9 weeks post-treatment.

Strictly for professional medical use, via direct intradermal injection into the eye area by a trained medical professional; do not inject intravascularly.

• HA (H-HA & L-HA): 192.00mg Total. Provides deep/surface hydration and blocks free radicals.
• Sodium Succinate: 96.00mg. Reinforces the skin barrier and stimulates metabolic processes.
• PDRN & PN: 5.00mg Total. Stimulates fibroblasts, accelerates cell renewal, and boosts wound healing.
• NAD+: Boosts cellular energy (ATP), promotes DNA repair, and targets senescent cells.
• Glutathione & Tranexamic Acid: Inhibits melanin, fades dark spots, and provides strong brightening effects.

A next-generation multi-functional skin booster combining highly effective ingredients for total anti-aging, whitening, and hydration, designed to leave no residues in the body with FDA proven safety.

• Brightening & Clarity: Reduction of hyperpigmentation, dark spots, and patches.
• Anti-Aging: Reduction of fine wrinkles, smoothing of skin texture, and stimulation of collagen.
• Hydration & Firmness: Volume replenishment and improvement in elasticity.
• Healing & Calm: Reduction of inflammation, calming of redness, and under-eye rejuvenation.

Cycle: 2-3 treatments at 1-month intervals.
Duration: Skin improvement and volume restoration effects are long-lasting, maintaining for 4 to 8 months.

Typically 24-36 months from the manufacturing date (unopened). Use immediately after mixing with saline. Discard any remaining solution after opening (single-use vial).

• Side Effects: Mild swelling, bruising, redness, and tenderness at the injection sites.
• Post-Care: Apply sunscreen regularly. Avoid heavy makeup immediately after the procedure, and refrain from exposure to extreme heat (saunas) or strenuous exercise during the initial recovery period.

It is a next-generation multi-functional skin booster for total anti-aging, brightening (reducing hyperpigmentation and dark spots), hydration, firmness, and skin healing.

HA (H-HA & L-HA, 192.00mg), Sodium Succinate (96.00mg), PDRN & PN (5.00mg), NAD+, and Glutathione & Tranexamic Acid for brightening.

Reconstitute by injecting 1mL of normal saline into the vial and shaking well before use. A cycle of 2-3 treatments at 1-month intervals gives effects lasting 4 to 8 months.

Strictly for professional medical use; deep dermis injections must only be performed by professionals and must not be intravascular.

It is manufactured by Healink Korea.

Collagenesis-Enabled Solubilized Active and Biodegradable Polymer technology enables PCL to be fully solubilized in water without microparticles, unlike traditional PCL fillers.

GOURI spreads naturally into the surrounding tissue due to its liquid nature and acts as a "Fundamental Anti-Aging" treatment. It biodegrades slowly while stimulating fibroblasts to synthesize new collagen (Neocollagenesis).

• Intense Collagenesis: Stimulation of the skin's natural collagen production.
• Skin Rejuvenation & Lifting: Improvements in skin elasticity, texture, and firmness.
• Wrinkle Reduction: Softens fine lines and deep wrinkles (e.g., crow's feet, marionette lines).
• Natural Volume: Restores volume loss gradually through natural collagen buildup.

Typically requires 2mL (2 syringes) per session for full-face coverage (1mL per side).

Can be safely used for the eye area due to its liquid spreadability.

Mild swelling (edema) is common for 2–3 days post-injection due to the collagenesis inflammatory response. Redness, bruising, or tenderness may occur.

• Avoid heavy makeup for 24 hours.
• Avoid sauna, alcohol, and strenuous exercise for 1 week.

What is GOURI used for?

GOURI is a liquid-type PCL injectable used as a fundamental anti-aging treatment. It stimulates natural collagen production, rejuvenates and lifts skin, softens fine lines and deep wrinkles, and restores natural volume gradually.

What is the key ingredient?

The key ingredient is Polycaprolactone (PCL) at 210mg/mL (21%), delivered as a fully solubilized, microparticle-free liquid using CESABP technology.

How long do results last?

Visual improvements often start within 1–2 weeks, and results typically last 6–12 months as the PCL degrades naturally. The standard cycle is 3 sessions spaced 4 weeks apart, with maintenance of 1–2 sessions every 6–12 months.

Who should administer GOURI?

GOURI is a Class III medical device administered by injection into the deep dermis to subcutaneous layer using a 30G to 35G needle, and should be administered by a qualified medical professional.

Who manufactures GOURI?

GOURI is manufactured by Dexlevo Inc.

Juveheal A features a dual growth factor action where EGF repairs the epidermis and FGF2 stimulates the dermis for improved skin density. Adenosine actively encourages collagen production to correct fine lines, while the Lotus water base provides deep hydration and soothing effects.

• Anti-Aging & Wrinkle Improvement: Specifically targets fine lines and deep wrinkles.
• Skin Vitality & Radiance: Restores a healthy glow to tired or aging skin.
• Elasticity Boost: Improves skin firmness and lifting effect.
• Deep Nutrition: Delivers concentrated nutrients to the skin layers.

Full face (especially areas with fine lines like eyes, forehead, nasolabial folds), Neck.

Ready-to-use liquid ampoule (tear off the plastic cap and aluminum seal to open).

Avoid direct sunlight, high temperature, and high humidity.

• Mild redness or irritation may occur, especially if used with MTS/microneedling (subsides within 1-2 days).

• Use a soothing mask (e.g., cooling sheet mask) after application.
• Apply sun protection.

What is Juveheal A used for?

Juveheal A is an anti-aging and wrinkle care ampoule. It targets fine lines and deep wrinkles, restores skin vitality and radiance, boosts elasticity and firmness, and delivers deep nutrition to the skin.

What are the key ingredients?

The primary active ingredients are Adenosine 0.04%, EGF (Rh-Oligopeptide-1), FGF2 (Rh-Polypeptide-1), and Hydrolyzed Collagen, with a Lotus Flower Water base.

How is it applied?

It is a ready-to-use liquid ampoule applied topically after cleansing. It is highly recommended for use with professional devices such as MTS, Derma Pen, or Electroporation to enhance absorption, typically 1 session per week.

Who should administer Juveheal A?

Juveheal A is for external (topical) use only. For enhanced absorption it is used with professional devices such as MTS, Derma Pen, or Electroporation under professional guidance.

Who manufactures Juveheal A?

Juveheal A is manufactured by J MEDICAL Inter Co., Ltd.