Skin Firmness and Lifting

The formula provides anti-apoptosis, anti-melanogenesis, anti-osteonecrosis, wound healing, anti-inflammation, tissue damage prevention, and bone regeneration effects. It utilizes DNA-based ingredients to reconstruct the dermal matrix and repair damaged cells. The released PN significantly stimulates the migration of human dermal fibroblasts, which plays a crucial role in tissue wound repair.

Addresses the root causes of aging by promoting skin regeneration and increasing dermal density, ultimately boosting collagen production.

• Improves overall skin tone, leaving it visibly brighter and smoother.
• Deeply moisturizes the skin with nourishing ingredients to maintain optimal hydration levels.
• Minimizes the appearance of pores by enhancing skin elasticity and hydration.
• Reduces roughness and pore volume while improving fine wrinkles and overall skin texture.

Specifically designed to target fine lines and loss of elasticity around the eyes.

Standard PN eye boosters generally recommend 3–4 sessions at 2–4 week intervals.

Store in a cool, dry place away from direct sunlight. Intended for single-use only; safely discard the syringe after application.

Injection site reactions such as mild swelling, redness, bruising, and temporary "embossing" (small bumps) around the delicate eye area.

• Apply broad-spectrum sunscreen.
• Avoid direct UV exposure, saunas, hot tubs, and strenuous physical activities for a few days post-treatment.

Hyaluronic Acid, Peptides, Botanical Extracts, and Aloe Vera.

• Fat Reduction: Actively targets and breaks down accumulated fat deposits under the eyes and effectively halts the regeneration of new fat.
• Skin Tightening: Hyaluronic acid and peptides work synergistically to provide deep hydration, promote skin elasticity, tighten under-eye tissue, and lift loose skin.

A clinically tested, non-surgical formula designed to provide quick and visible results with minimal downtime and no significant swelling or bruising.

Dissolves sagging fat deposits, reduces puffiness and dark circles, tightens and lifts loose under-eye skin, and smooths fine lines and wrinkles.

Subcutaneous injection. Depth should be 2~6mm into the fat layer, superficial fascia layer, and under the skin around the eyes. (Can also be applied topically with gentle massage or via microneedling, depending on the practitioner's protocol).

For eye bag treatment, use 1 bottle (2mL) per session, equating to 1mL per side. Utilize 5 injection points per side with a spacing of 0.3~0.5mm between points. Total injection volume must not exceed 5mL.

Single-use vials. Keep away from direct sunlight.

Clinically tested to cause no significant swelling, bruising, or pain, though mild, temporary injection-site reactions may occur.

• Apply ice or a medical repair mask within 30 minutes after treatment to soothe the skin.
• Do not wash or bathe the treated area for 1 week.
• Refrain from strenuous exercise, alcohol consumption, and saunas for 1 week.
• Avoid spicy foods, seafood, and direct sun exposure.
• Do not use ointments, skincare products, or cosmetics on the treated area to prevent infection.

It is a fat-dissolving and skin-tightening booster that dissolves sagging fat deposits, reduces puffiness and dark circles, tightens loose under-eye skin, and smooths fine lines.

Hyaluronic Acid, Peptides, Botanical Extracts, and Aloe Vera.

It provides quick, noticeable results in a short time, with long-lasting effects on puffiness and skin firmness.

Professional application is highly recommended, via subcutaneous injection 2~6mm into the fat layer around the eyes by a qualified practitioner.

Advanced Cross-linked HA creates a stable 3D matrix to lock in moisture and restore elasticity, while Glutathione acts as a powerful antioxidant to brighten skin tone, fade pigmentation, and detoxify tired skin.

• Deep & Long-Lasting Hydration: Locks in moisture for months.
• Radiance & Tone: Brightens skin tone and fades pigmentation (Whitening effect).
• Elasticity & Plumping: Restores firmness and smooths fine lines.
• Detox & Protection: Fights oxidative stress and revitalizes congested skin.

Single-use vials. Discard any remaining solution after opening.

It is a whitening and hydration skin booster that brightens skin tone, fades pigmentation, and delivers deep long-lasting hydration for the face and body.

Cross-linked Hyaluronic Acid (10 mg/mL) and Glutathione (1 mg/mL), combining a moisture-locking HA matrix with antioxidant brightening.

A standard course is 5 sessions total, spaced 2–3 weeks apart.

For external/professional use only, injected by a qualified practitioner using micropapular, nappage, or linear/retrograde techniques.

It is manufactured by Phace Global Co., Ltd.

A Dual-Action system where HA provides immediate deep hydration and plumping, while PDRN enhances cellular regeneration, DNA synthesis, and tissue repair (anti-inflammatory).

• Deep Hydration & Glow: Instantly hydrated skin with a natural radiant glow.
• Skin Regeneration: Repairs damaged skin barrier and improves overall skin health.
• Texture & Pores: Smoothes skin texture and tightens enlarged pores.
• Anti-Aging: Improves elasticity and firmness while softening fine lines.
• Tone Correction: Brighter, more even skin tone with reduced redness.

Single-use vials. Discard any remaining solution immediately after opening.

Mild swelling, redness, or papules (bumps) at injection sites are common and typically resolve within 24–48 hours.

It is a skin booster for deep hydration, skin regeneration, texture and pore improvement, and anti-aging on the full face, especially dry, dull, or sensitive skin.

PDRN 2% (Salmon DNA) and non-crosslinked Hyaluronic Acid 17mg/mL, working as a dual-action system for hydration and cellular repair.

Instant glow after Session 1, visible pore tightening and elasticity boost by Session 3, and full rejuvenation effects by Session 5 (5 sessions, 2 weeks apart).

For external/professional use only, applied via papule injection or microneedling (MTS) by a qualified practitioner.

It is manufactured by Phace Global Co., Ltd.

• PDRN (Sodium DNA): Extracted from salmon sperm. Highly compatible with human DNA for cell regeneration.
• Human Adipose-derived Stem Cell Extract: Contains nutrients and growth factors (EGF, FGF, HGF) to produce collagen.
• Hyaluronic Acid: Provides deep moisturization.

Functions as a "New Cell Repairing Factor." The ingredients optimize fibroblastic functions in the dermis, creating an ideal ecosystem to boost core cellular functions and activate tissue regeneration.

• Hydration: +132% improvement in moisture levels.
• Skin Elasticity: +103% improvement in firmness.
• Wrinkle Reduction: +72% reduction in wrinkles and fine lines.
• Tone & Texture: Enhances oil/water balance, softens skin, and provides a whitening effect.

1 Session = 5 Procedures over 3 months.
1st to 3rd Procedure: Spaced 1–2 weeks apart.
4th and 5th Procedure: Spaced 1 month apart (for maintenance).

Discard any remaining product within 7 days after opening due to the lack of preservatives. Keep away from direct sunlight.

• Mild redness, swelling, or pinpoint bleeding temporarily associated with the MTS/injection method. (PDRN is highly compatible with human DNA, minimizing immunological side effects).
• Apply soothing masks or regenerative creams post-procedure.
• Strict sun protection is required to prevent pigmentation during the healing phase.

It is a skin booster for total anti-aging and regeneration, improving hydration, elasticity, wrinkles, and tone on dull, sagging, and wrinkled facial skin.

PDRN (Sodium DNA from salmon sperm), Human Adipose-derived Stem Cell Extract with growth factors, and Hyaluronic Acid, within a composite of 43 active ingredients.

One session is 5 procedures over 3 months: the 1st to 3rd spaced 1–2 weeks apart, and the 4th and 5th spaced 1 month apart for maintenance.

For professional use only, applied via Mesotherapy injection or MTS under strict aseptic conditions since the formula is preservative-free.

High-purity HA attracts water molecules to the dermis, restoring moisture balance immediately while stimulating fibroblasts to promote endogenous collagen synthesis.

• Intensive Moisturizing: Restores dry and dehydrated skin (Hydro-lifting).
• Skin Rejuvenation: Improves overall skin radiance and brightness (Glow effect).
• Texture Improvement: Tightens pores and smoothes fine lines/wrinkles.
• Elasticity Restoration: Enhances skin firmness through collagen stimulation.

Supplied as ready-to-use pre-filled syringes. No mixing required.

Store away from direct sunlight. Do not freeze. Do not use if the package is damaged.

• Mild redness (erythema) or swelling
• Bruising or tenderness at the injection site
• Symptoms usually resolve within 1–3 days

• Avoid heavy makeup for at least 24 hours.
• Avoid saunas, steam rooms, and excessive heat for 1 week.
• Apply sunscreen diligently.

It is used for intensive moisturizing (hydro-lifting), skin rejuvenation and radiance, texture improvement with pore tightening and fine-line smoothing, and elasticity restoration through collagen stimulation.

Its primary active ingredient is Hyaluronic Acid (HA) 15mg/mL (1.5%), buffered with Phosphate Buffered Saline (PBS) pH 7.0.

Visible improvement appears in 1–2 weeks and effects last 3–6 months. A course of 3–4 sessions at 2–3 week intervals is recommended.

It is a medical device for use by licensed practitioners only and should be administered by a qualified professional.

REGENOVUE Aqua Shine is manufactured by NeoGenesis Co., Ltd.

NAD+ is a vital coenzyme present in all living cells, crucial for mitochondrial function and ATP (energy) production. Applied to the skin, it facilitates cellular energy metabolism, promotes DNA repair, delays cellular senescence, and activates fibroblasts. This molecular-level rejuvenation helps restore the structural integrity of the dermis.

• Deep cellular regeneration.
• Powerful anti-aging and wrinkle reduction.
• Improvement of skin elasticity.
• Restoration of skin vitality and radiance.
• Strengthening of the skin barrier.

Face, neck, décolletage, and the back of the hands (areas primarily showing signs of photoaging and intrinsic aging).

Standard NAD+ skin booster protocols generally recommend 3–5 sessions at 2–4 week intervals.

Store in a cool, dry place away from direct sunlight (typically 1–30°C or refrigerated at 2–8°C, depending on the exact formulation state).

Intended for professional, single-use application. Open vials should be used immediately to prevent oxidation or contamination.

Mild redness (erythema), localized swelling, pinpoint bruising, or tenderness at the injection or microneedling sites.

• Avoid direct sun exposure and apply broad-spectrum sunscreen diligently.
• Refrain from saunas, hot tubs, swimming, and strenuous exercise for at least 48 hours post-treatment.

• H-HA (High molecular weight HA): 67.5mg
• L-HA (Low molecular weight HA): 67.5mg
• PDRN (Polydeoxyribonucleotide): 5mg
• PN (Polynucleotide): 5mg

H-HA & L-HA provide intense moisture, enhance skin elasticity, and maintain long-lasting volume. PDRN & PN promote cell regeneration, offer anti-inflammatory effects, enhance wound healing, and repair broken collagen and elastin fibers.

• Hydration & Volume: Intense moisturizing and long-lasting volume support.
• Rejuvenation: Wrinkle reduction, collagen & elastin regeneration.
• Healing & Tone: Anti-inflammatory wound healing, whitening, and scar/acne improvement.

Cycle: 3 treatments at 2-week intervals.
Onset: Rapid onset with PDRN/PN action visible in 1-2 weeks.
Duration: Overall effect lasts 4 to 8 months.

Single-use vial. Discard any remaining solution after opening.

• Common Effects: Mild swelling, redness, bruising, tenderness, or temporary papules (bumps) at injection sites.
• Post-Care: Avoid heavy makeup for 24 hours. Avoid extreme heat (saunas, hot baths) and strenuous exercise for a few days. Apply sunscreen regularly.

It is a skin booster for deep hydration, skin texture improvement, wrinkle reduction, wound healing, and overall cell regeneration across the full face, neck, and back of hand.

A complex of H-HA and L-HA (67.5mg each) plus PDRN (5mg) and PN (5mg) per 5mL, combining HA hydration with PDRN/PN cell regeneration.

The overall effect lasts 4 to 8 months, with PDRN/PN action visible in 1-2 weeks, following a cycle of 3 treatments at 2-week intervals.

It is strictly for professional medical use and must not be injected intravascularly.

It is manufactured by Healink Korea.

• Barrier Formation: PN forms a physical barrier on the skin to block environmental stressors and maintain optimal moisture levels.
• Fibroblast Activation: Activates fibroblasts to stimulate collagen synthesis, restoring skin structure and elasticity from within.
• Anti-inflammatory Action: Provides anti-inflammatory support to improve the overall skin environment and support tissue recovery.

• Restores oil-water balance and reduces sebum secretion for improved skin texture
• Replenishes elastic fibers including collagen, enhancing the skin's self-healing capacity
• Promotes wound and scar healing
• Effectively improves dryness, pigmentation, wrinkles, and skin sagging

Provides an extended maintenance and retention period attributed to the long DNA chain structure of the PN, which slows degradation and prolongs efficacy in the skin.

PLLA microparticles stimulate the body's natural collagen production (neocollagenesis) by activating fibroblasts. As the PLLA is gradually absorbed and metabolized by the body, the newly formed collagen restores lost facial volume and improves overall skin elasticity.

Composed of a biodegradable and biocompatible synthetic polymer designed to act as a biostimulator rather than a traditional volumizing filler.

• Gradual and natural-looking volume restoration.
• Deep wrinkle correction.
• Long-term collagen regeneration.
• Improvement of overall skin tone and texture.

Facial contouring, deep wrinkles (e.g., nasolabial folds, marionette lines), sunken cheeks, temples, and jawline.

Results appear gradually over 4 to 6 weeks as new collagen is synthesized. The volumizing and rejuvenating effects are long-lasting, typically persisting for 18 to 24 months.

Store in a cool, dry place away from direct sunlight. Once reconstituted, the product should be used within the recommended timeframe according to standard PLLA protocols.

Patients are typically advised to massage the treated area gently for 5 minutes, 5 times a day, for 5 days to ensure even product distribution and prevent the formation of subcutaneous nodules.

Mild swelling, bruising, redness, and tenderness at the injection sites.

It is a PLLA collagen biostimulator for gradual, natural-looking volume restoration, deep wrinkle correction, and long-term collagen regeneration for facial contouring.

Poly-L-Lactic Acid (PLLA), a biodegradable, biocompatible synthetic polymer that stimulates the body's natural collagen production (neocollagenesis).

It requires proper reconstitution with Sterile Water for Injection (SWFI) prior to the procedure to ensure an even suspension of PLLA particles.

Strictly for professional medical use, via deep dermal or subcutaneous injection; do not inject intravascularly or into the superficial epidermis.

PLA (Poly-L-Lactic Acid), PN (Polynucleotides), NAD-(NMN), HA (Hyaluronic Acid), Niacinamide, Vitamin B2, and Succinic Acid.

A multi-modal biostimulator that shifts beyond simple filling by delivering instant improvements in skin quality alongside long-lasting structural remodeling and cellular repair.

• Immediate deep hydration and radiant glow.
• Long-term structural volumization and increased dermal density.
• Skin regeneration and enhanced cellular energy.
• Brightening and antioxidant protection.

• Face: Neck wrinkles, forehead lines, frown lines, crow's feet, and marionette lines.
• Eyes: Dark circles, eye wrinkles, and eye bags.
• Body: Wrinkle care, tightening, cellulite, stretch marks, and brightening for areas like hands, knees, elbows, and armpits.

Onset: Immediate hydration and optical smoothness from HA.
Duration: Gradual accumulation of new collagen and elastin over weeks to months, providing long-term volumization.

Typically 24-36 months from the manufacturing date. Once reconstituted, the solution should be used immediately.

• Side Effects: Mild swelling, redness, bruising, or tenderness at the application sites.
• Post-Care: Apply sunscreen diligently. Avoid excessive heat exposure (e.g., saunas) and strenuous physical activity for a few days post-treatment.

It is a multi-modal biostimulator for immediate hydration and glow, long-term structural volumization, skin regeneration, and brightening across the face, eyes, and body.

PLA (Poly-L-Lactic Acid), PN (Polynucleotides), NAD-(NMN), HA (Hyaluronic Acid), Niacinamide, Vitamin B2, and Succinic Acid.

Shake the vial by hand for 1 minute to reconstitute the lyophilized powder; once reconstituted, the solution should be used immediately.

Strictly for professional medical and aesthetic use, administered into the dermal/subcutaneous layer; do not inject intravascularly.

• 1 Immediate (CMC Phase): Immediately after injection, the dermis layer is filled with CMC gel, providing instant volume and supporting the surrounding tissue.
• 2 Long-term (PLA Phase): As the CMC gel is gradually absorbed and dissolved, the PLA microspheres remain in place and stimulate cells to produce new collagen — delivering natural wrinkle improvement from the inside out.

• HMT (Homologous Microsphere Technology): Creates perfectly spherical and uniform PLA particles precisely sized at 30–50 µm for consistent, predictable results.
• High Molecular Weight: 190,000–250,000 Da — ensures structural integrity and sustained collagen stimulation over time.
• Eco-Friendly & Biodegradable: No BDDE residue. PLA material fully degrades within 1–2 years.

• Acts as a natural collagen stimulator to dramatically restore volume
• Improves deep wrinkles and gradually rejuvenates overall skin texture
• Delivers dual-phase action: immediate volumizing followed by sustained collagen regeneration

• 1 Add 1.4 mL of WFI (Water For Injection) to the vial.
• 2 Allow to dissolve at room temperature. Standard dissolution time is approximately 1 hour (full dissolution confirmed within 60–90 minutes).
• 3 Confirm beads are completely dissolved before proceeding to injection to ensure even particle suspension.

• Do not freeze.
• Must be properly reconstituted prior to injection to ensure even particle suspension.

• PN (Polynucleotide): Fills in and strengthens thin, stretched skin while actively regenerating the skin barrier at a cellular level.
• HA (Hyaluronic Acid, 1.4M Da): Protects the skin barrier and provides intensive, long-lasting moisture retention.
• MGF Multi Growth Factor Complex: A biomimetic blend of 40 active ingredients optimized for skin cell regeneration, tissue repair, and metabolic support.

• Skin moisturization and deep hydration
• Texture improvement and pore tightening
• Elasticity improvement and anti-aging effects
• Skin regeneration and wound healing support
• Sebum reduction for balanced skin condition

• 1 Prepare the skin for absorption using the appropriate aesthetic device (Fraxel Laser / EL / Sonophor).
• 2 Apply PN BOOSTER evenly to the treatment area.
• 3 Apply REVS Gel Mask and leave on for 10–15 minutes.
• 4 Finish by applying REVS Repairing Serum to lock in active ingredients.

• Protect from direct sunlight.
• Do not freeze.

• 1 Apply REVS Hydrating Gel Mask for 10–15 minutes to provide immediate soothing relief to irritated skin.
• 2 Follow with REVS Repairing Serum to hold active ingredients onto the skin and support recovery.

The Wellsfil series features a monophasic gel structure designed to provide smooth injection, uniform tissue integration, and structural stability. The series includes 0.3% lidocaine to minimize patient discomfort during the procedure. It is available in three viscoelastic variants to target different depths of the skin and address various aesthetic concerns, from superficial wrinkles to deep facial contouring.

• Polynucleotide (PN) 1%: Deeply hydrates the skin, regulates sebum secretion, and softens and brightens skin texture.
• Polydeoxyribonucleotide (PDRN) 1%: Promotes blood circulation, stimulates fibroblast growth to activate collagen and elastin synthesis, and repairs damaged tissues through strong anti-inflammatory effects.

Multi-molecular weight Hyaluronic Acid, Peptide complex, Amino acid blend, and Antioxidants.

Formulated with natural ingredients that have a 97% match to human DNA, effectively preventing allergic and toxic reactions while promoting profound cellular regeneration.

• Intensive Hydration: Restores deep moisture balance.
• Skin Regeneration: Overall skin regeneration, elasticity restoration, and tone enhancement.
• Texture & Clarity: Reduction of fine wrinkles, pore reduction, and alleviation of acne scars.
• Pigmentation: Improvement of melasma and hyperpigmentation.

Microneedling Therapy System (MTS), Mesotherapy (dermal injection), micro-deposit, or grid injection techniques. Efficacy is significantly enhanced when combined with laser treatments or sonophoresis.

Single-use vials. Open and use immediately.

Mild swelling, redness, bruising, and tenderness at the injection site.

• Apply sunscreen diligently.
• Avoid direct sunlight, excessive heat (e.g., saunas), and harsh environments for a few days post-treatment.

It is a cellular skin booster for intensive hydration, skin regeneration and elasticity, fine wrinkle and pore reduction, acne scar improvement, and pigmentation correction.

Polynucleotide (PN) 1% and Polydeoxyribonucleotide (PDRN) 1%, supported by multi-molecular weight Hyaluronic Acid, a peptide complex, amino acids, and antioxidants.

There is immediate hydration and improvement upon administration, with deep cellular regeneration effects lasting up to 12 months, over a course of 3 to 6 sessions at 2 to 4-week intervals.

Strictly for professional medical and aesthetic use via MTS, mesotherapy, micro-deposit, or grid injection; intravascular injection is strictly prohibited.

It is manufactured by Cosmoderma, Inc.