Skin Recovery and Regeneration

• A2A Receptor Activation: PDRN binds to adenosine A2A receptors to exert anti-inflammatory effects and repair damaged tissues.
• Salvage Pathway: Provides nucleosides (DNA precursors) via the salvage pathway to promote rapid DNA synthesis and cell proliferation.
• Growth Factor Stimulation: Promotes the secretion of VEGF and other growth factors to aid angiogenesis and wound healing.

• Tissue Regeneration: Repairs damaged skin barrier, improves skin thickness, and treats ligament/tendon injuries.
• Pore & Scar Reduction: Diminishes acne scars and tightens pores.
• Rapid Healing: Accelerates wound healing and provides anti-inflammatory support.
• Texture Improvement: Enhances overall skin texture and hydration.

• Medical (Systemic/Local): Intramuscular (IM) or Subcutaneous (SC) injection.
• Aesthetic (Off-label): Intradermal (ID) injection (Mesotherapy) or MTS (Microneedling) application to the face.

• Mild pain, redness, or swelling at the injection site.
• Bruising from the needle insertion.

What is Rejuvenex Forte used for?

Rejuvenex Forte is a high-concentration PDRN solution used for tissue regeneration, pore and scar reduction, rapid wound healing with anti-inflammatory support, and overall skin texture improvement.

What is the key ingredient?

The primary active ingredient is Polydeoxyribonucleotide Sodium (PDRN) at 14.06mg per 2.5mL, derived from salmon DNA.

How long do results last?

Visible skin improvements are often noted after 3–4 sessions, and tissue regeneration effects are cumulative. The typical course is 1 session per week for 3–5 weeks.

Who should administer Rejuvenex Forte?

It is an ethical drug (ETC) administered by injection, including intramuscular or subcutaneous injection and aesthetic intradermal (mesotherapy) or MTS application, and should be administered by a qualified medical professional.

Who manufactures Rejuvenex Forte?

Rejuvenex Forte is manufactured by PharmaResearch Co., Ltd.

The minimal cross-linking technology creates a structure that remains in the dermis longer than non-cross-linked HA. This provides sustained deep hydration, structural renewal of the skin matrix, and bio-stimulation of endogenous collagen.

• Long-lasting Deep Hydration: Improved moisture retention compared to non-cross-linked boosters.
• Skin Lifting & Tightening: Improves skin elasticity and firmness.
• Wrinkle Reduction: Smoothes fine lines, crow's feet, and micro-wrinkles.
• Skin Tone Improvement: Brightens complexion and reduces dullness.
• Pore Refinement: Helps to narrow enlarged pores.

Supplied as ready-to-use pre-filled syringes. Ensure strict aseptic technique during administration.

Store away from direct sunlight and avoid extreme heat. Do not freeze. Single-use only.

• Erythema (redness) or swelling at injection site
• Pain, itching, or bruising
• Symptoms usually resolve within a few days

• Avoid makeup for 12–24 hours.
• Avoid saunas, steam rooms, and intense exercise for 1 week.
• Apply sun protection diligently.

It is used for long-lasting deep hydration, skin lifting and tightening, wrinkle reduction, skin tone improvement, and pore refinement.

Its primary active ingredient is Hyaluronic Acid (HA) 15mg/mL (minimally cross-linked), buffered with Phosphate Buffered Saline (PBS) pH 7.0.

Visible results appear in 1–2 weeks and effects last 6–8 months. A course of 3–4 sessions spaced 3–4 weeks apart is recommended.

It is intended for professional use by licensed medical practitioners only.

REGENOVUE Aqua Shine Plus is manufactured by NeoGenesis Co., Ltd.

• Sodium Hyaluronate (HA): 1.0% (10mg/mL) – Non-crosslinked, high-purity.
• Polynucleotide (PN): 0.5% – DNA-derived agent for tissue regeneration.

• Glutathione: Brightening and antioxidant protection.
• Peptide Complex: Acetyl Hexapeptide-8, Palmitoyl Tripeptide-5, 4, 7, Collagen Peptides.
• Adenosine: Functional ingredient for wrinkle improvement.

This product combines intense hydration with tissue regeneration. HA draws moisture into the dermis to restore volume, while PN (Salmon DNA) activates self-regeneration power. Simultaneously, Glutathione inhibits melanin for brightening, and the Peptide complex supports the formula's fine-line care.

• Intense and deep skin hydration (Hydro-lifting effect)
• Skin barrier strengthening and tissue regeneration
• Skin tone improvement and brightening (Radiance/Glow)
• Reduction of fine lines and wrinkles (Anti-aging)
• Pore tightening and texture refinement

The product comes in a ready-to-use pre-filled syringe; no dilution is required.

• Keep away from direct sunlight and heat sources.
• Do not freeze.
• Single-use only; discard any remaining solution after opening.

• Temporary redness or swelling
• Bruising or needle marks at injection sites
• Symptoms usually subside within 1–3 days

• Avoid heavy makeup for 24 hours.
• Avoid saunas, steam rooms, and strenuous exercise for a few days after treatment.

It is used for intense deep skin hydration (hydro-lifting), skin barrier strengthening and tissue regeneration, brightening, reduction of fine lines and wrinkles, and pore tightening with texture refinement.

Its primary active ingredients are Sodium Hyaluronate (HA) 1.0% (10mg/mL, non-crosslinked) and Polynucleotide (PN) 0.5% (salmon DNA-derived).

A course of 3–5 sessions spaced 3–4 weeks apart is recommended, with maintenance every 3–6 months.

It is a medical device intended for professional use only and should be administered by a qualified practitioner.

REJUBEAU Aqua Bomb is manufactured by TRACLE Inc.

• High molecular weight HA: 67.5mg
• Low molecular weight HA: 67.5mg
• Polydeoxyribonucleotide (PDRN): 5.0mg
• Polynucleotide (PN): 5.0mg

Cellular Rejuvenation: PDRN and PN (derived from salmon DNA) repair broken collagen and elastin fibers, stimulate fibroblasts to generate new tissue, normalize fibroblast size, and provide anti-inflammatory and wound-healing effects. Dual Hydration: H-HA and L-HA synergistically provide deep and surface hydration, enhance elasticity, and maintain volume.

• Intense Under-Eye Rejuvenation: Specifically targeted treatment for the delicate eye area.
• Deep Hydration & Volume: Replenishes moisture and restores sagging, hollow areas.
• Fine Lines & Wrinkles: Softens and reduces the appearance of wrinkles, including crow's feet.
• Regeneration & Calming: Repairs damaged tissue, improves elasticity, and provides anti-inflammatory healing.

Typically 24–36 months from the manufacturing date (Unopened). Single-use only. Discard any remaining product.

Mild swelling, bruising, redness, tenderness, or temporary papules (small bumps) at the injection sites.

It is a skin booster for intense under-eye rejuvenation, treating tear troughs, crow's feet, under-eye hollows, and eyelids with deep hydration and wrinkle reduction.

High and low molecular weight HA (67.5mg each) plus PDRN (5.0mg) and PN (5.0mg) derived from salmon DNA.

Significant visible improvements, including deep hydration and wrinkle reduction, are typically noted prominently around 9 weeks post-treatment.

Strictly for professional medical use, via direct intradermal injection into the eye area by a trained medical professional; do not inject intravascularly.

Polynucleotide (derived from salmon DNA) regenerates tissue and improves skin density in the dermis, while Hyaluronic Acid provides deep hydration. Glutathione acts as an antioxidant to brighten the skin, and Collagen Peptides stimulate elasticity.

Targeted eye rejuvenation including dark circle reduction and brightening. It provides fine wrinkle correction (Crow's feet), strengthens the skin barrier, and offers deep hydration with improved elasticity.

Under-eye area (Tear troughs), Crow's feet, Neckline, Back of hands, and thin wrinkles on the face.

Ready-to-use pre-filled syringe (No reconstitution required).

Store away from direct sunlight. The product is for single-use only.

• Temporary redness at the injection site
• Swelling or bruising
• Tenderness

• Avoid heavy makeup for a few hours post-injection
• Avoid touching the treated area

It is used for targeted eye rejuvenation, including dark circle reduction, brightening, fine wrinkle correction (Crow's feet), skin barrier strengthening, and deep hydration with improved elasticity.

Its primary active ingredients are Polynucleotide (PN) 1% (derived from salmon DNA) and Sodium Hyaluronate (HA) 0.5%.

It is administered by injection (mesotherapy / intradermal injection) using a 32G or 33G (4mm length) needle, with 3 sessions recommended at 20–30 day intervals.

It is for professional use only and should be administered by a qualified practitioner.

REJUBEAU Eye Deal is manufactured by TRACLE INC.

The CMC gel provides an immediate physical lifting effect upon injection. As the gel is absorbed, CaHA microspheres form a scaffold that stimulates fibroblasts to produce new natural collagen and elastin (Neocollagenesis) for long-term structural support.

• Volume Restoration: Fills deep wrinkles and restores lost facial volume.
• Skin Tightening & Lifting: Improves elasticity through collagen production.
• Wrinkle Correction: Smoothes deep folds like nasolabial folds and marionette lines.
• Skin Quality Improvement: Enhances hydration and barrier function (when used diluted).

• Store in a cool, dry place away from direct sunlight.
• Do not freeze.
• Single-use only.

• Swelling, bruising, redness, pain, or itching at injection site.
• Nodules may occur if not massaged properly or injected too superficially.

• Massage the treated area if recommended by the provider.
• Avoid heavy makeup and intense heat (sauna) for 24 hours.

NAD+ is a vital coenzyme present in all living cells, crucial for mitochondrial function and ATP (energy) production. Applied to the skin, it facilitates cellular energy metabolism, promotes DNA repair, delays cellular senescence, and activates fibroblasts. This molecular-level rejuvenation helps restore the structural integrity of the dermis.

• Deep cellular regeneration.
• Powerful anti-aging and wrinkle reduction.
• Improvement of skin elasticity.
• Restoration of skin vitality and radiance.
• Strengthening of the skin barrier.

Face, neck, décolletage, and the back of the hands (areas primarily showing signs of photoaging and intrinsic aging).

Standard NAD+ skin booster protocols generally recommend 3–5 sessions at 2–4 week intervals.

Store in a cool, dry place away from direct sunlight (typically 1–30°C or refrigerated at 2–8°C, depending on the exact formulation state).

Intended for professional, single-use application. Open vials should be used immediately to prevent oxidation or contamination.

Mild redness (erythema), localized swelling, pinpoint bruising, or tenderness at the injection or microneedling sites.

• Avoid direct sun exposure and apply broad-spectrum sunscreen diligently.
• Refrain from saunas, hot tubs, swimming, and strenuous exercise for at least 48 hours post-treatment.

• PLLA (Poly-L-lactic acid): 400mg. Acts as a bio-stimulator triggering fibroblast activity for long-lasting neocollagenesis.
• H-HA (High-molecular-weight HA): 60mg.
• L-HA (Low-molecular-weight HA): 60mg. Provides immediate hydration and acts as a safe carrier/suspension agent for PLLA particles.

Microporous Sphere Technology: Utilizes spherical PLLA particles with internal pores, maximizing the surface area for higher collagen/elastin production and allowing for smoother injections. CMC & Mannitol Free: Uses HA instead of CMC/Mannitol for suspension, adding immediate volumizing impact.

• Deep Volume Replenishment: Immediate volumization (via HA) for large body areas.
• Collagenesis: Sustained stimulation and generation of collagen under the skin (via PLLA).
• Skin Improvement: Smoothing of skin texture, reduction of fine wrinkles, and improved elasticity.

Standard Cycle: 2 to 3 sessions at 1-month intervals.
Duration: Long-lasting PLLA effects maintained for up to 24 months.

To prevent the formation of subcutaneous nodules (granulomas), practitioners strictly recommend the "5-5-5 Rule" for patients: Massage the treated area for 5 minutes, 5 times a day, for 5 days post-treatment to ensure even particle distribution.

Juveheal A features a dual growth factor action where EGF repairs the epidermis and FGF2 stimulates the dermis for improved skin density. Adenosine actively encourages collagen production to correct fine lines, while the Lotus water base provides deep hydration and soothing effects.

• Anti-Aging & Wrinkle Improvement: Specifically targets fine lines and deep wrinkles.
• Skin Vitality & Radiance: Restores a healthy glow to tired or aging skin.
• Elasticity Boost: Improves skin firmness and lifting effect.
• Deep Nutrition: Delivers concentrated nutrients to the skin layers.

Full face (especially areas with fine lines like eyes, forehead, nasolabial folds), Neck.

Ready-to-use liquid ampoule (tear off the plastic cap and aluminum seal to open).

Avoid direct sunlight, high temperature, and high humidity.

• Mild redness or irritation may occur, especially if used with MTS/microneedling (subsides within 1-2 days).

• Use a soothing mask (e.g., cooling sheet mask) after application.
• Apply sun protection.

What is Juveheal A used for?

Juveheal A is an anti-aging and wrinkle care ampoule. It targets fine lines and deep wrinkles, restores skin vitality and radiance, boosts elasticity and firmness, and delivers deep nutrition to the skin.

What are the key ingredients?

The primary active ingredients are Adenosine 0.04%, EGF (Rh-Oligopeptide-1), FGF2 (Rh-Polypeptide-1), and Hydrolyzed Collagen, with a Lotus Flower Water base.

How is it applied?

It is a ready-to-use liquid ampoule applied topically after cleansing. It is highly recommended for use with professional devices such as MTS, Derma Pen, or Electroporation to enhance absorption, typically 1 session per week.

Who should administer Juveheal A?

Juveheal A is for external (topical) use only. For enhanced absorption it is used with professional devices such as MTS, Derma Pen, or Electroporation under professional guidance.

Who manufactures Juveheal A?

Juveheal A is manufactured by J MEDICAL Inter Co., Ltd.

• Ultra-Pure Plant Exosome: 500 Million nano-sized particles/ml for deep cellular absorption.
• Premium PDRN: Derived from Alaskan salmon to boost cellular repair and circulation.

Exosomes stimulate follicle regeneration and reduce inflammation, while PDRN boosts scalp recovery. The added Peptide & Enzyme complex strengthens roots and balances the scalp environment.

• Hair Growth & Density: Reactivates dormant follicles; 89% of users noticed denser, stronger hair.
• Reduced Shedding: 93% reported visibly less hair shedding.
• Scalp Health: Calms inflammation and strengthens the moisture barrier for improved comfort.

• 1. Prepare: Cleanse and disinfect scalp. Apply 1/2 vial to create a moist glide.
• 2. MTS Procedure: Glide sterile cartridge (depth 0.5-1.2mm) in straight/overlapping passes.
• 3. Absorb: Apply remaining 1/2 vial and lightly massage for 1-2 minutes.
• 4. Soothe: Finish by applying 'Exosome Nurturing Solution' (Tube) to lock in actives.

Store away from direct sunlight. Vials are for single use; do not store open vials due to lack of preservatives.

• Mild redness, heating sensation, or slight swelling (subsides within hours).

• Avoid washing hair for at least 4-6 hours post-treatment.
• Avoid saunas, heavy sweating, or swimming for 24 hours.

A synergistic effect of Hydration (HA), Regeneration (PDRN), and Cellular Recharging (NAD+). It acts as a bio-stimulator to activate the skin's natural healing and energy production cycles.

• Deep Hydration & Glow: Provides an instant moisture boost and "water glow" radiance.
• Skin Regeneration: Repairs damaged skin barrier and improves texture.
• Cellular Energy: NAD+ boosts ATP production for enhanced cell renewal.
• Anti-Aging: Softens fine lines, improves elasticity, and tightens pores.

Rejuva Healer S is marketed as a 4th Generation Skin Booster. It eliminates the need to layer multiple products by combining the benefits of HA (1st Gen), PDRN (2nd Gen), and Exosomes (3rd Gen) with the added cellular energy boost of NAD+.

What is Rejuva Healer S used for?

Rejuva Healer S is a 4th generation NAD+ skin booster used for deep hydration and glow, skin regeneration and barrier repair, cellular energy boosting, and anti-aging (softening fine lines, improving elasticity, and tightening pores).

What are the key ingredients?

The primary active ingredients are PDRN 2% (Salmon DNA), Hyaluronic Acid 17mg/mL (non-crosslinked), and NAD+ (Nicotinamide Adenine Dinucleotide).

How long do results last?

Hydration and glow are visible immediately after the 1st session, while texture, pore, and elasticity improvements become prominent after the 3rd session. The standard cycle is 3 to 5 sessions spaced 2–3 weeks apart.

Who should administer Rejuva Healer S?

It is for external/professional use only and is administered by injection (papule or nappage technique) using a 30G × 4mm or 32G needle, and should be administered by a qualified professional.

Who manufactures Rejuva Healer S?

Rejuva Healer S is supplied by Phace Global / Esta Global.

• c-PDRN (Cosmetic Polydeoxyribonucleotide): Hydrolyzed DNA from salmon, optimized for skin absorption to repair damaged cells.
• Sodium Hyaluronate (HA): High-quality European hyaluronic acid for intense hydration.

A Double Effect system where HA provides immediate deep hydration and volume support, while c-PDRN penetrates the barrier to stimulate biological regeneration and collagen synthesis.

• Deep Hydration (Hydro-Lifting): Relieves inner skin dryness and provides a radiant "water glow."
• Skin Regeneration: Repairs skin barrier damaged by external irritation or aesthetic procedures (e.g., lasers).
• Texture Improvement: Softens rough skin texture and improves elasticity.
• Soothing: Calms sensitive and tired skin.

Apply to cleansed skin. Highly recommended for use with aesthetic devices such as MTS (Microneedling), Electroporation, or Iontophoresis to enhance penetration.

• Intensive Care: 3–5 sessions at 1–2 week intervals.
• Maintenance: 1 session every 1–2 months.

Mild redness or irritation may occur if used with aggressive MTS, usually subsiding within 24 hours.

What is Rejuvenex Hydro Essence used for?

Rejuvenex Hydro Essence is a hydro-lifting skin booster used for deep hydration and a radiant water glow, skin barrier regeneration (including post-procedure repair), texture improvement, and soothing sensitive or tired skin.

What are the key ingredients?

The primary active ingredients are c-PDRN (Cosmetic Polydeoxyribonucleotide, hydrolyzed salmon DNA) and Sodium Hyaluronate (Hyaluronic Acid).

How is it applied?

It comes in a ready-to-use pre-filled syringe and is applied to cleansed skin. It is highly recommended for use with aesthetic devices such as MTS (Microneedling), Electroporation, or Iontophoresis. Intensive care is 3–5 sessions at 1–2 week intervals.

Who should administer Rejuvenex Hydro Essence?

It is for external (topical) use only. When combined with aesthetic devices such as MTS, Electroporation, or Iontophoresis, it should be used under professional guidance.

Who manufactures Rejuvenex Hydro Essence?

Rejuvenex Hydro Essence is manufactured by PharmaResearch Co., Ltd.